Results 121 to 130 of about 170,801 (252)

Organoid Models to Study Human Infectious Diseases

Cell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu, Dan Chen, Xinzhi Yang, Liuliu Yang, Yuling Han   +4 more
wiley   +1 more source

Features of Diagnostics and Complex Approach to Therapy of Herpetic Keratitis

Oftalʹmologiâ, 2019
Objective. To determine the characteristics of drug therapy in patients with herpetic keratitis (HK), based on laboratory diagnosis.Material and methods. 49 patients with clinical symptoms of HK were included in the study.
E. A. Kleshcheva, S. A. Kochergin, Yu. B. Slonimskiy   +2 more
doaj   +1 more source

CRISPR Technology in Disease Management: An Updated Review of Clinical Translation and Therapeutic Potential

Cell Proliferation, EarlyView.
CRISPR‐Cas systems offer transformative genome editing capabilities for precise manipulation of cellular genes. This enables two main therapeutic avenues: ex vivo modification of patient cells for re‐transplantation or direct in vivo gene targeting via advanced delivery methods.
Bahareh Farasati Far, Marziyeh Akbari, Mohammad Amin Habibi, Morteza Katavand, Sherko Nasseri   +4 more
wiley   +1 more source

Parvovirus B19‐associated myocarditis in children: A systematic review of clinical features, management and outcomes

European Journal of Clinical Investigation, EarlyView.
This systematic review summarizes clinical features, diagnostic strategies and outcomes of paediatric myocarditis associated with Parvovirus B19. Affected children are typically under 3 years old and often present with fulminant symptoms, severe cardiac dysfunction and a high need for ICU‐level support or mechanical circulatory assistance.
Giacomo Veronese, Giada Colombo, Andrea Garascia, Rachele Adorisio, Ezio Bonanomi, Enrico Ammirati   +5 more
wiley   +1 more source

Vitamin D deficiency or supplementation and the risk of human herpesvirus infections or reactivation: a systematic review protocol

BMJ Open, 2019
Introduction Human herpesviruses induce lifelong latent infections and may reactivate as the immune system deteriorates. Recent studies have suggested that vitamin D, an essential element of bone health, may have some effect of protecting against ...
Charlotte Warren-Gash, Liang-Yu Lin, Ketaki Bhate, Sinéad Langan   +3 more
doaj   +1 more source

Pathogenic, Molecular, and Immunological Properties of a Virus Associated with Sea Turtle Fibropapillomatosis. Phase II : Viral Pathogenesis and Development of Diagnostic Assays [PDF]

, 2000
Research conducted under this RWO from July 1, 1997 through June 30, 2000 has provided important new information about the pathogenesis, virology, and immunology of marine turtle fibropapillomatosis. In particular, we have provided strong evidence for
Bjorndal, Karen A., Bolten, Alan, Brown, Daniel R., Coberley, Sadie, Ehrhart, Llewellyn, Herbst, Lawrence H., Klein, Paul A., Lackovich, Joel K., Moretti, Ritchie H.   +8 more
core  

Acute neurologic presentation of a 2‐year‐old standardbred colt with multicentric diffuse large B cell lymphoma

Equine Veterinary Education, EarlyView.
Summary Lymphoma in horses is uncommon and rarely diagnosed as a cause of ataxia. This case report describes a 2‐year‐old Standardbred cryptorchid colt who presented with acute onset of grade 3–4/5 spinal ataxia in all four limbs, with the hindlimbs more severely affected than forelimbs and severe proprioceptive deficits.
K. MacMillan, J. Burns, E. John, M. Buote   +3 more
wiley   +1 more source

Features of the course of viral hepatitis A in a child with persistent mixed herpesvirus infection

Лечащий Врач
Background. Today in the structure of viral hepatitis viral hepatitis A takes the lead position, the course of typical forms is usually favorable. Over the last few years, however, the frequency of viral hepatitis A has become higher, with increased ...
E. G. Khramtsova, M. D. Subbotina
doaj   +1 more source

Herpesvirus 6 Infection and Febrile Seizures

Pediatric Neurology Briefs, 1996
The link between human herpesvirus-6 (HHV-6) and other viruses and febrile convulsions (FC) in 65 children (mean age 18 months) with a first episode of simple FC (Group 1) compared to 24 children (mean age 19 months) with a febrile syndrome without FC ...
J Gordon Millichap
doaj   +1 more source

Additional file 2: of Comparative genomic, transcriptomic, and proteomic reannotation of human herpesvirus 6

, 2018
Figure S1. Resequencing of select iciHHV-6B specimens confirms identical sequences among unrelated patients. Samples from select iciHHV-6B specimens with identical sequences were re-extracted, re-prepared and re-sequenced from original patient material to rule out contamination or a sample specimen switch during the sequencing process.
Greninger, Alexander, Knudsen, Giselle, Pavitra Roychoudhury, Hanson, Derek, Sedlak, Ruth, Xie, Hong, Guan, Jon, Nguyen, Thuy, Peddu, Vikas, Boeckh, Michael, Meei-Li Huang, Cook, Linda, Depledge, Daniel, Zerr, Danielle, Koelle, David, Soren Gantt, Yoshikawa, Tetsushi, Caserta, Mary, Hill, Joshua, Jerome, Keith   +19 more
openaire   +1 more source