Results 131 to 140 of about 170,801 (252)

A guide to heat shock factors as multifunctional transcriptional regulators

The FEBS Journal, EarlyView.
The heat shock factors (HSFs) are evolutionarily conserved transcription factors best known as regulators of molecular chaperone genes in response to heat shock and other protein‐damaging stresses. Vertebrate HSFs, HSF1‐5, HSFX, and HSFY, are implicated in various physiological and pathological processes, including organismal development and cancer ...
Hendrik S. E. Hästbacka, Alejandro J. Da Silva, Lea Sistonen, Eva Henriksson   +3 more
wiley   +1 more source

Epidemiological investigation into abortion in farmed red deer in New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Sciences at Massey University, Palmerston North, New Zealand [PDF]

, 2016
Reproductive performance in rising two-year-old (R2) and mixed-aged (MA) adult hinds is suboptimal in farmed red deer in New Zealand due to failure to conceive, fetal loss, and perinatal and postnatal mortality.
Patel, Kandarp Khodidas
core  

Solid organ transplantation in people with HIV: Outcomes, obstacles and opportunities

HIV Medicine, EarlyView.
Abstract Objective People with HIV experience disparate access to solid organ transplantation (SOT), despite mounting evidence for comparable outcomes. This review aims to understand the outcomes following SOT, obstacles to SOT and opportunities to improve access and outcomes following SOT.
David W. J. Griffin, J. H. McMahon, D. A. Ruschena, J. F. Hoy   +3 more
wiley   +1 more source

Mycobacterium avium Subsp. paratuberculosis and Human Endogenous Retrovirus in Italian Patients With Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS)

Immunology, EarlyView.
Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a recognised gastrointestinal disorder. Mycobacterium avium subspecies paratuberculosis (MAP) is implicated in IBD pathogenesis. Persistent exposure and active infections by MAP may contribute to the unsilencing of human endogenous retroviruses (HERV ...
Stefano Ruberto, Alfredo Santovito, Gian P. Caviglia, Marta Noli, Davide Cossu, Davide G. Ribaldone, Demis Pitoni, Simona Frara, Elisa Tribocco, Chiara Rosso, Marta Guriglia, Ilaria Cossu, Pier A. Tovo, Massimiliano Bergallo, Leonardo A. Sechi   +14 more
wiley   +1 more source

Seroprevalence of Antibodies against Human Herpesvirus 6 in the Quebec City Area

Canadian Journal of Infectious Diseases, 1992
Seroprevalence of antibodies against human herpesvirus 6 was determined in a sample of 303 randomly selected individuals from the Quebec City area. The influence of different variables on antibody litres was also evaluated.
Louise Deschênes, Jean R Joly, Michel Couillard, Gilles Richer   +3 more
doaj   +1 more source

The Role of Human Herpesvirus 8 in Diabetes Mellitus Type 2: State of the Art and a Medical Hypothesis

, 2015
Diabetes is a common chronic disease due to an altered glucose metabolism, caused by the quantitative and/or qualitative dysfunction of the insulin hormone. Two types of diabetes are recognized: juvenile diabetes, or type 1, which has an autoimmune origin, and adult diabetes, or type 2 (DMT2), which covers 90-95 % of all diabetic patients.The causes of
openaire   +3 more sources

Herpesvirus Simplex Virus‐1 Exploits Inflammation to Infect Periodontal Stem Cells and Disrupt Lineage Commitment

Journal of Periodontal Research, EarlyView.
HSV‐1 infects oral mesenchymal stem cells both in vitro and in vivo to dysregulate their lineage commitment. An inflamed gingival environment increases susceptibility to HSV‐1 infection, which further elevates proinflammatory cytokine levels and exacerbates alveolar bone loss.
Araceli Valverde, Raza Ali Naqvi, Yinghua Chen, Alireza Moshaverinia, Anne George, Deepak Shukla, Gloria Martinez, Gabriella Chapa, Salvador Nares, Afsar R. Naqvi   +9 more
wiley   +1 more source

Practical Application of Disease Risk Assessment in Native Species Reintroductions: A Case Study of a European Wildcat (Felis silvestris) Population Reinforcement in the Cairngorms National Park

Mammal Review, EarlyView.
Disease risk assessment was conducted for the Saving Wildcats reintroduction project of captive‐bred European Wildcats (Felis silvestris) to the Cairngorms National Park. Hazards were identified, and appropriate pre‐and post‐release mitigation strategies were identified and implemented, illustrating the direct conservation application and significance ...
Alice Bacon, Beatriz S. G. Alves, Simon Girling, Adam Naylor   +3 more
wiley   +1 more source

Enhancing melatonin biosynthesis in crops through synthetic genetic circuits: A strategy for nutritional fortification in soybean and stress resistance in cotton

Plant Biotechnology Journal, EarlyView.
Summary Melatonin has gained considerable prominence in the treatment of insomnia that significantly impacts one‐third of the global population. The production of melatonin remains challenging due to limitations in current methods. Thus, there is an urgent need for developing more efficient and innovative production techniques.
Yue Shi, Zegang Han, Wanying Zhang, Lu He, Zhuolin Shi, Xiaowei Ma, Ji Zhou, Zhanfeng Si, Yan Hu, Tianzhen Zhang   +9 more
wiley   +1 more source

Characterization of a continuous feline mammary epithelial cell line susceptible to feline epitheliotropic viruses. [PDF]

, 2009
Mucosal epithelial cells are the primary targets for many common viral pathogens of cats. Viral infection of epithelia can damage or disrupt the epithelial barrier that protects underlying tissues.
Heymer, Anna, Liu, Hongwei, Millon, Lee, Ossiboff, Robert J, Parker, John SL, Pesavento, Patricia, Stucker, Karla M, van der List, Deborah, Wood, Jason   +8 more
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