Results 141 to 150 of about 635,179 (242)

RNAi Regulator C3PO Promotes Arbovirus Infection in Insect Vectors

Advanced Science, Volume 13, Issue 4, 19 January 2026.
RNA interference (RNAi) is vital for eukaryotes to defend against virus infection. The C3PO complex takes part in RNAi but its role in regulating viral infection remains unclear. This work finds that insect C3PO facilitates arbovirus replication by degrading precursors of miRNAs, especially miR‐971‐3p.
Yan Xiao, Tianyu Guan, Qianfeng Xia, Chen Chen, Qian Wang, Lan Luo, Hong Lu, Feng Cui   +7 more
wiley   +1 more source

Impact of Herpesvirus Detection via Metagenomic Next-Generation Sequencing in Patients with Lower Respiratory Tract Infections

Infection and Drug Resistance
Huihui Zhang,1,* Xiaojing Zhang,2,* Yafeng Zheng,2,* Xiao Gu,1 Zhongming Fu,1 Wei Gai,2 Huaying Wang1 1Department of Respiratory and Critical Care Medicine, The Affiliated People’s Hospital of Ningbo University, Yinzhou People’s Hospital ...
Zhang H, Zhang X, Zheng Y, Gu X, Fu Z, Gai W, Wang H   +6 more
doaj  

The Clinical Characteristics and Treatment of Patients With Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy (GFAP‐A): A Retrospective Study of 29 Patients

Brain and Behavior, Volume 16, Issue 1, January 2026.
A retrospective analysis of clinical features, treatment, and outcome of 29 patients with autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A). Cerebrospinal fluid (CSF) pressure, CSF nucleated cell count, CSF protein levels, CSF chloride, serum thyroid dysfunction, and abnormal blood cytokine levels correlated with disease severity but ...
Xuewei Yang, Lanling Jin, Chanhong Shi, Hongwei Yue, Hongfei He, Wenli Zhu, Ruili Wei   +6 more
wiley   +1 more source

A Flavonoid‐Rich Extract of Scoparia dulcis L. Exhibits Antiviral Activity against Herpes Virus Type 1

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT This study investigated the phytochemical profile, cytotoxicity, and anti‐herpetic activity of the hydroethanolic extract from Scoparia dulcis L. aerial parts. Mass spectrometry revealed the presence of 15 compounds. The extract showed low cytotoxicity in Vero cells, maintaining over 80% viability at concentrations up to 250 µg/mL.
Francisco Leandro Medeiros de Lucena Jales, Emerson Michell da Silva Siqueira, Renato Dantas‐Medeiros, Edilane Rodrigues Dantas de Araújo, Jovelina Samara Ferreira Alves, Hugo Alexandre de Oliveira Rocha, Norberto Peporine Lopes, Leandro de Santis Ferreira, Emanuella de Aragão Tavares, Silvana Maria Zucolotto   +9 more
wiley   +1 more source

Three Challenging Cases of Autoimmune Encephalitis: A Case‐Series and a Review of the Literature

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT This manuscript highlights the importance of considering autoimmune encephalitis in patients presenting with multisystem symptoms that cannot be explained by a single neurological condition. Early inclusion of autoimmune encephalitis in the differential diagnosis can help avoid unnecessary treatments and reduce overall healthcare costs.
Mohammad Ali Bahramy, Pegah Pedramfard, Reza Shahriarirad   +2 more
wiley   +1 more source

Herpes Simplex Virus Infection With Multiple Cerebral Hemorrhages: A Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Herpes simplex virus (HSV) infection may trigger rare vascular complications that lead to multiple cerebral hemorrhages. This case emphasizes considering HSV in unexplained cerebral hemorrhage among immunocompromised individuals with systemic symptoms, as timely antiviral treatment effectively improves clinical outcomes.
Zhongzhan Wu, Fangfang Liu, Fugui Wang, Jie Li, Houqing Lu   +4 more
wiley   +1 more source

Human herpesvirus 7 and the risk of developing multiple sclerosis. [PDF]

Brain Commun
Ingvarsson J, Grut V, Gustafsson R, Biström M, Lambert L, Michels BE, Bergström T, Flamand L, Waterboer T, Sundström P.   +9 more
europepmc   +1 more source

Toward Anti‐Herpesviral PROTACs: Assessing the Challenges for Targeted Protein Degradation on the Example of Kaposi's Sarcoma‐Associated Herpesvirus Latency‐Associated Nuclear Antigen

ChemMedChem, Volume 21, Issue 1, January 2026.
It is attempted to employ proteolysis‐targeting chimeras‐based targeted protein degradation to the viral protein “Latency‐associated Nuclear Antigen” from Kaposi's sarcoma‐associated herpesvirus. While ternary complex formation is detected via native mass spectrometry, protein degradation is not observed, presumably due to insufficient permeability ...
Aylin Berwanger, Saskia Catherina Stein, Sarah Brandner, Andreas Martin Kany, Sebastian Heinz, Brigitta Loretz, Claus‐Michael Lehr, Anna Katharina Herta Hirsch, Frederik Lermyte, Thomas Friedrich Schulz, Martin Empting   +10 more
wiley   +1 more source

Practical implications of the World Health Organization Reporting System for Lymph Node, Spleen, and Thymus Cytopathology: Categories and ancillary testing for subtyping of hematolymphoid tumors on FNA biopsy cytopathology using a pattern‐based approach

Cancer Cytopathology, Volume 134, Issue 1, January 2026.
Abstract The objective of the recently published World Health Organization Reporting System for Lymph Node, Spleen, and Thymus Cytopathology (WHO system) is to standardize the diagnostic approach to fine‐needle aspiration biopsies of hematolymphoid tissues.
Mats Ehinger, Maria Calaminici, Immacolata Cozzolino, Pio Zeppa, Andrew S. Field   +4 more
wiley   +1 more source

Human herpesvirus 7 induced aseptic meningitis in an immunocompetent adult presenting with unusual neurological symptoms: a case report. [PDF]

Virol J
Nguyen LCA, Nguyen PMA, Nguyen THN.
europepmc   +1 more source