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Interleukin-2 inhibits the replication of human herpesvirus-6 in mature thymocytes

Virology, 1990
Human herpesvirus-6 (HHV-6) is a recently identified T lymphotropic virus. We have examined the ability of HHV-6 to replicate in mature and immature human thymocytes. Infection of both cell populations revealed that only mitogen-activated mature thymocytes could support efficient virus replication. Because interleukin-2 (IL-2) plays a central role in T
E, Roffman, N, Frenkel
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Serological study of human herpesvirus simplex 1 and bovine herpesvirus 1, 2, and 4 in Kansas cattle

The Bovine Practitioner, 1989
A total of 589 beef cattle and 466 dairy cattle were tested for antibodies to herpes simplex virus-1 (HSV-1) and bovine herpes virus-1, 2, and 4 (BHV) using the indirect fluorescent antibody test (IFAT). In the beef cattle, prevalence of antibodies to HSV-1, BHV-1, 2, and 4 was 34.8%, 67.9%, 36.5% and 12.4% respectively, and in the dairy cattle ...
Phillips, R. M., Nassar, R. F.
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Chapter 2 The epidemiology of human herpesvirus-6

1992
Publisher Summary Human herpesvirus-6 (HHV-6) was first isolated from six patients with lymphoproliferative disease or immunosuppressive disorders. This chapter discusses the techniques to investigate the epidemiology and determine HHV-6 role in human disease. Some studies report that infection with HHV-6 usually occurs in early childhood.
Paul H. Levine   +2 more
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Acquisition of the human adeno-associated virus type-2 rep gene by human herpesvirus type-6

Nature, 1991
Human herpesvirus type-6 (HHV-6) is a recently isolated herpesvirus which is highly prevalent in adult populations around the world. HHV-6 was first isolated from the peripheral blood of six individuals with lymphoproliferative disorders, two of whom were also infected with human immunodeficiency virus.
B J, Thomson, S, Efstathiou, R W, Honess
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Ex vivo protocol for testing virus survival on human skin: experiments with herpesvirus 2

Applied and Environmental Microbiology, 1996
We report an ex vivo method, which uses pieces of human skin excised during routine plastic surgery, for testing survival of hazardous pathogens. Using this procedure, we compared the survival of human herpesvirus 2 on human skin and on metal disks. At the physiological skin temperature of 32 degrees C, the half-life of the virus on skin was 1.44 h ...
M L, Graham   +2 more
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Effect of Herpesvirus hominis Type 2 on human cervical epithelium: Scanning electron microscopic observations

American Journal of Obstetrics and Gynecology, 1972
Abstract The clinical effects of Herpesvirus hominis Type 2 on the human cervix and vagina have been known for centuries. However, only recently has interest increased with the possible correlation of herpes infections with diseases of the fetus and neonate and cervical cancer.
G D, Wilbanks, J A, Campbell
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A retrospective review of mucocutaneous infections by human herpesvirus 1 and 2 in an urban population in Malaysia.

The Medical journal of Malaysia, 2003
This is a 10-year retrospective review of mucocutaneous infection by human herpesvirus 1 (HHV1) and human herpesvirus 2 (HHV2) carried out by the virus diagnostic unit of University Malaya Medical Centre (UMMC). A total of 504 specimens from UMMC and a private clinic in the same city (KLSC) were tested; 198 samples from patients with oral lesions and ...
Hooi, P.S.   +4 more
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Prevalence of Human Herpesvirus 8 Infection in Patients With Type 2 Diabetes and Blood Donors

Journal of Medical Virology
ABSTRACT Human herpesvirus 8 (HHV‐8) positivity rates vary across regions. The rates are higher in immunosuppressed patients. There is a potential association between HHV‐8 and type 2 diabetes. The aim of this study is to determine the prevalence of HHV‐8 infection in type 2 diabetes patients and healthy blood ...
Eylül Beren Tanık   +5 more
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Generation and characterization of a monoclonal antibody specific for human herpesvirus 6 variant A immediate–early 2 protein

Journal of Clinical Virology, 2003
Two variants (A and B) of human herpesvirus 6 (HHV-6) can be isolated from humans, with each variant having unique biological properties. HHV-6 variant typing is mainly done following amplification of viral genomic DNA followed by restriction endonuclease digestion.
Suzie, Arsenault   +3 more
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Immunofluorescent assay of herpesvirus type 1 and type 2 antibodies in rabbit and human sera

Archiv f�r die gesamte Virusforschung, 1971
The immunofluorescent antibody technique was used to assay type-specific herpes simplex virus antibodies. Antibody responses were studied in three groups of patients: children with primary herpetic infections, neonates with generalized type 2 infection and adults with genital herpes infections.
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