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Interleukin-2 inhibits the replication of human herpesvirus-6 in mature thymocytes

Virology, 1990
Human herpesvirus-6 (HHV-6) is a recently identified T lymphotropic virus. We have examined the ability of HHV-6 to replicate in mature and immature human thymocytes. Infection of both cell populations revealed that only mitogen-activated mature thymocytes could support efficient virus replication. Because interleukin-2 (IL-2) plays a central role in T
Ehud Roffman, Niza Frenkel
openaire   +3 more sources

Serological study of human herpesvirus simplex 1 and bovine herpesvirus 1, 2, and 4 in Kansas cattle

The Bovine Practitioner, 1989
A total of 589 beef cattle and 466 dairy cattle were tested for antibodies to herpes simplex virus-1 (HSV-1) and bovine herpes virus-1, 2, and 4 (BHV) using the indirect fluorescent antibody test (IFAT). In the beef cattle, prevalence of antibodies to HSV-1, BHV-1, 2, and 4 was 34.8%, 67.9%, 36.5% and 12.4% respectively, and in the dairy cattle ...
R. M. Phillips, R. F. Nassar
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Cells transformed by Human Herpesvirus Type 2 transcribe Virus-specific RNA Sequences shared by Herpesvirus Types 1 and 2

Nature New Biology, 1973
RECENT studies associate herpesviruses with neoplastic diseases of several animal species and man (see review by Klein1). Direct evidence links herpesviruses with the aetiology of Marek's disease of chickens2 and with the Lucke adenocarcinoma of the frog3–6 and less direct but persuasive data associate the Epstein-Barr herpesvirus with human Burkitt's ...
Helen Thornton   +2 more
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Chapter 2 The epidemiology of human herpesvirus-6

1992
Publisher Summary Human herpesvirus-6 (HHV-6) was first isolated from six patients with lymphoproliferative disease or immunosuppressive disorders. This chapter discusses the techniques to investigate the epidemiology and determine HHV-6 role in human disease. Some studies report that infection with HHV-6 usually occurs in early childhood.
Paul H. Levine   +2 more
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Acquisition of the human adeno-associated virus type-2 rep gene by human herpesvirus type-6

Nature, 1991
Human herpesvirus type-6 (HHV-6) is a recently isolated herpesvirus which is highly prevalent in adult populations around the world. HHV-6 was first isolated from the peripheral blood of six individuals with lymphoproliferative disorders, two of whom were also infected with human immunodeficiency virus.
R. W. Honess   +2 more
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Effect of Herpesvirus hominis Type 2 on human cervical epithelium: Scanning electron microscopic observations

American Journal of Obstetrics and Gynecology, 1972
Abstract The clinical effects of Herpesvirus hominis Type 2 on the human cervix and vagina have been known for centuries. However, only recently has interest increased with the possible correlation of herpes infections with diseases of the fetus and neonate and cervical cancer.
George D. Wilbanks, James A. Campbell
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Clinically Mild Encephalopathy With a Reversible Splenial Lesion Type 2 Caused by Human Herpesvirus 6 Infection

Pediatric Neurology, 2020
Clinically mild encephalopathy with a reversible splenial lesion (MERS) is the second commonest cause of encephalopathy. Several pathogens have been detected in patients with MERS type 2, such as influenza A and B, but little is known about the proportion of cases of MERS type 2 with this pathogenesis. Human herpesvirus 6 (HHV6) is the second commonest
Fumikazu Sano   +5 more
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Enforced expression of humanbcl‐2in CD4+T cells enhances human herpesvirus 7 replication and induction of cytopathic effects

European Journal of Immunology, 1998
The cytopathic effects (CPE) resulting from the infection of CD4+ T cells by human herpes-virus 7 (HHV-7) comprises two major mechanisms: generation of large polyploid cells, which eventually undergo necrotic lysis, and apoptosis, predominantly occurring in small mononucleated cells.
SECCHIERO, Paola   +7 more
openaire   +5 more sources

Co-infection of human herpesvirus type 2 (HHV-2) and human immunodeficiency virus (HIV) among pregnant women in Rio de Janeiro, Brazil

AIDS Care, 2017
Pregnant women who are infected with the Human Immunodeficiency Virus (HIV) are particularly vulnerable to severe and recurrent infections with Human Herpesvirus 2 (HHV-2). Neonatal transmission of HHV-2 has been associated with malformations and neurological sequelae in infants, which makes it very important to perform antenatal monitoring for genital
José Henrique Pilotto   +5 more
openaire   +2 more sources

Generation and characterization of a monoclonal antibody specific for human herpesvirus 6 variant A immediate–early 2 protein

Journal of Clinical Virology, 2003
Two variants (A and B) of human herpesvirus 6 (HHV-6) can be isolated from humans, with each variant having unique biological properties. HHV-6 variant typing is mainly done following amplification of viral genomic DNA followed by restriction endonuclease digestion.
Suzie Arsenault   +3 more
openaire   +3 more sources

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