Results 51 to 60 of about 613,530 (223)

Machine‐Learning Microfluidic Minute‐Scale Microorganism Metrics Monitoring(M6)

Advanced Science, EarlyView.
ABSTRACT On‐site monitoring of microorganisms remains challenging because of low concentrations, strong background interference, and dynamic aerosol diffusion, particularly for aerosol‐transmitted pathogens. Here, we report a rapid detection platform that integrates a Puri‐focusing microfluidic chip, electrochemical impedance spectroscopy (EIS), and ...
Ning Yang, Jiahao Ding, Si Chen, Lijie Yan, Shichao Ding, Lavonda Li, Junyi Sun, Haodong Liu, Tongge Li, Ning Liu, Mingji Wei, Xiaoyong Zhu, Xiaobo Zou, Shouqi Yuan, Xingcai Zhang   +14 more
wiley   +1 more source

Pathology of Kaposi's sarcoma-associated herpesvirus infection

Frontiers in Microbiology, 2011
Kaposi’s sarcoma-associated herpesvirus (KSHV, human herpesvirus 8, HHV-8) is a human herpesvirus, classified as a gamma-herpesvirus. KSHV is detected in Kaposi’s sarcoma (KS), primary effusion lymphoma (PEL), and some cases of multicentric Castleman’s ...
Hitomi eFukumoto, Hitomi eFukumoto, Takayuki eKanno, Hideki eHasegawa, Harutaka eKatano   +4 more
doaj   +1 more source

The genome of herpesvirus papio 2 is closely related to the genomes of human herpes simplex viruses

Journal of General Virology, 2003
Infection of baboons (Papio species) with herpesvirus papio 2 (HVP-2) produces a disease that is clinically similar to herpes simplex virus (HSV-1 and HSV-2) infection of humans. The development of a primate model of simplexvirus infection based on HVP-2 would provide a powerful resource to study virus biology and test vaccine strategies.
John E, Bigger, David W, Martin
openaire   +2 more sources

Crystal Structure of the DNA-Binding Domain of Human Herpesvirus 6A Immediate Early Protein 2 [PDF]

Journal of Virology, 2017
ABSTRACT Immediate early proteins of human herpesvirus 6A (HHV-6A) are expressed at the outset of lytic infection and thereby regulate viral gene expression. Immediate early protein 2 (IE2) of HHV-6A is a transactivator that drives a variety of promoters.
Mitsuhiro, Nishimura, Junjie, Wang, Aika, Wakata, Kento, Sakamoto, Yasuko, Mori   +4 more
openaire   +2 more sources

The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1

Advanced Science, EarlyView.
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth, Christoph F. Jacob, Alexandra Nguyen, Mandy Beyer, Andreas O. Mieland, Mario Dejung, Jia‐Xuan Chen, Walburgis Brenner, Christina Ehrhardt, Andreas Henke, Oliver H. Krämer   +10 more
wiley   +1 more source

Herpesvirus-associated acute urticaria: an age matched case-control study. [PDF]

PLoS ONE, 2013
BACKGROUND: Acute and recurrent acute urticaria are often associated with multiple factors including infections and recent data suggest a role for herpesviruses.
Arianna Mareri, Stuart P Adler, Giovanni Nigro   +2 more
doaj   +1 more source

A Humanized Anti‐gD Broadly Neutralizing Antibody Confers Complete Post‐Exposure Protection against Pseudorabies Virus

Advanced Science, EarlyView.
Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun, Jianbo Liu, Shi‐Jia Xu, Meng‐Xin Wang, Hongliang Zhang, Yanhe Zhang, Zhi‐Jun Tian, Jin‐Mei Peng, Xin Yin, Tong‐Qing An, Xue‐Hui Cai, Yan‐Dong Tang   +11 more
wiley   +1 more source

CNS INFECTIONS CAUSED BY VIRUSES OF THE HERPESVIRIDAE FAMILY: CASE ANALYSIS IN A TERTIARY INFECTIOUS DISEASES CENTER

Brazilian Journal of Infectious Diseases
Introduction/Objectives: The Herpesviridae family includes viruses with latency capacity, such as HSV-1, HSV-2, VZV, CMV, and Human herpesvirus 6, which can cause neurological manifestations such as meningitis, encephalitis, and encephalomyelitis.
Luís Arthur Brasil Gadelha Farias, Lorena Alves Brito, Bruno Cavalcante Fales de Brito Alves, José Leonardo da Silveira Morais, Osvaldo Mariano Viana Neto, Ednaldo Pereira Lima Sobrinho, Tânia Mara Silva Coelho, Maura Salaroli de Oliveira, Lauro Vieira Perdigão Neto, Antonio Silva Lima Neto   +9 more
doaj   +1 more source

Characterization of the immediate-early 2 protein of human herpesvirus 6, a promiscuous transcriptional activator

Virology, 2003
In the present work we report the cloning of a full-length cDNA encoding the immediate-early (IE) 2 protein from human herpesvirus 6 (HHV-6) variant A (GS strain). The transcript is 4690 nucleotides long and composed of 5 exons. Translation initiation occurs within the third exon and proceeds to the end of U86.
Gravel, Annie, Tomoiu, Andru, Cloutier, Nathalie, Gosselin, Jean, Flamand, Louis   +4 more
openaire   +2 more sources

Late Cytomegalovirus Infections After Allogeneic Hematopoietic Cell Transplant

American Journal of Hematology, EarlyView.
ABSTRACT Graft versus host disease (GVHD) prophylaxis with posttransplant cyclophosphamide (ptCY) and cytomegalovirus (CMV) prophylaxis with letermovir have changed the clinical epidemiology of CMV infection. We studied the incidence, risk factors for, and outcomes of CMV infection after Day + 90 of allogeneic hematopoietic cell transplant (alloHCT ...
George L. Chen, Roland Bassett, Rohtesh S. Mehta, Betul Oran, Fareed Khawaja, Ella J. Ariza‐Heredia, Yosra Aljawai, Amanda Olson, May Daher, Portia Smallbone, Katayoun Rezvani, Partow Kebriaei, Uday Popat, Richard Champlin, Roy F. Chemaly, Elizabeth J. Shpall   +15 more
wiley   +1 more source