Results 81 to 90 of about 1,529,869 (227)

Seroprevalence of 13 common pathogens in a rapidly growing U.S. minority population: Mexican Americans from San Antonio, TX

BMC Research Notes, 2011
BackgroundInfection risks vary among individuals and between populations. Here we present information on the seroprevalence of 13 common infectious agents in a San Antonio-based sample of Mexican Americans.
R. Rubicz, C. Leach, E. Kraig, N. Dhurandhar, B. Grubbs, J. Blangero, R. Yolken, H. Göring   +7 more
semanticscholar   +1 more source

Cryptococcal meningitis due to Cryptococcus neoformans VNI in a koala (Phascolarctos cinereus) with progressive neurological disease

Australian Veterinary Journal, EarlyView.
Nearly all cases of cryptococcosis in koalas are caused by Cryptococcus gattii species complex. A rare case of meningitis due to Cryptococcus neoformans VNI/AFLP1 (abbreviated VNI) is described in a koala with nasal colonisation by both species complexes.
A Teh, R Crisman, E Dwars, R Malik, LH de Miranda, W Meyer, M Krockenberger   +6 more
wiley   +1 more source

Human Herpesvirus-6 Reactivation, Mitochondrial Fragmentation, and the Coordination of Antiviral and Metabolic Phenotypes in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

ImmunoHorizons, 2020
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a multifactorial disorder with many possible triggers. Human herpesvirus (HHV)–6 and HHV-7 are two infectious triggers for which evidence has been growing.
Philipp Schreiner, T. Harrer, C. Scheibenbogen, S. Lamer, A. Schlosser, R. Naviaux, B. Prusty   +6 more
semanticscholar   +1 more source

Herpes simplex virus‐1 infection alters microtubule‐associated protein Tau splicing and promotes Tau pathology in neural models of Alzheimer's disease

Brain Pathology, EarlyView.
HSV‐1 infection alters MAPT splicing and promotes Tau pathology in neural models of Alzheimer's disease. HSV‐1 infection in brain organoids and neuronal models increase 4R‐MAPT splicing and Tau hyperphosphorylation. HSV‐1 ICP27 is both necessary and sufficient for inducing these changes highlighting the potential role of HSV‐1 in Alzheimer's disease ...
Emmanuel C. Ijezie, Michael J. Miller, Celine Hardy, Ava R. Jarvis, Timothy F. Czajka, Lianna D'Brant, Natasha Rugenstein, Adam Waickman, Eain Murphy, David C. Butler   +9 more
wiley   +1 more source

Evolutionary History of Endogenous Human Herpesvirus 6 Reflects Human Migration out of Africa

Molecular biology and evolution, 2020
Human herpesvirus 6A and 6B (HHV-6) can integrate into the germline, and as a result, ∼70 million people harbor the genome of one of these viruses in every cell of their body. Until now, it has been largely unknown if 1) these integrations are ancient, 2)
A. Aswad, Giulia Aimola, D. Wight, Pavitra Roychoudhury, Cosima Zimmermann, Joshua A. Hill, D. Lassner, H. Xie, Meei-Li W Huang, N. Parrish, H. Schultheiss, C. Venturini, S. Lager, Gordon C. S. Smith, D. S. Charnock-Jones, J. Breuer, A. Greninger, B. Kaufer   +17 more
semanticscholar   +1 more source

A 37‐Year Retrospective Analysis Reveals a High Rate of Cutaneous Angiosarcoma of the Scalp in Okinawa, Japan

Cancer Science, Volume 116, Issue 4, Page 1059-1067, April 2025.
A 37‐year retrospective analysis has revealed an exceptionally high rate of angiosarcoma of the scalp in Okinawa, Japan. This study represents the first identification of Okinawa as a hotspot for this rare cancer, the epidemiology of which has been insufficiently studied.
Aoi Ohira, Daisuke Utsumi, Ryoko Awazawa, Nobutake Yagi, Tsuyoshi Awazawa, Sayaka Yamaguchi, Teruki Yanagi, Kenzo Takahashi   +7 more
wiley   +1 more source

T cells from newly diagnosed multiple sclerosis patients have enhanced responsiveness to CD46 activation

Clinical and Experimental Neuroimmunology, EarlyView.
Abstract Objective To evaluate the responsiveness of T cells from newly diagnosed multiple sclerosis (MS) patients to CD46 co‐stimulation, a membrane co‐factor protein potentially involved in MS pathogenesis. Methods T cells from MS patients and non‐diseased symptomatic controls (SC) were activated in vitro with or without αCD46 antibody co‐stimulation.
Linda Sundvall, Litten S. Rossen, Vivien R. Schack, Bettina Bundgaard, Peter V. Rasmussen, Thor Petersen, Per Höllsberg   +6 more
wiley   +1 more source

Human herpesvirus 6A induces apoptosis of HSB-2 cells via a mitochondrion-related caspase pathway

Journal of Biomedical Research, 2010
Apoptosis plays an important role in the pathogenesis of viral infections. In this study, we investigated the cell death processes during productive HHV-6A infection and the underlying mechanisms. Annexin V-PI staining and electron microscopy indicated that HHV-6A is a strong inducer of apoptosis.
Lingyun Li, Fang Wang, Jing Chi, Genyan Liu, Chun Zhang, Dandan Guo, Kun Yao, Feng Zhou   +7 more
openaire   +3 more sources

Features of Human Herpesvirus-6A and -6B Entry

Advances in Virology, 2012
Human herpesvirus-6 (HHV-6) is a T lymphotropic herpesvirus belonging to the Betaherpesvirinae subfamily. HHV-6 was long classified into variants A and B (HHV-6A and HHV-6B); however, recently, HHV-6A and HHV-6B were reclassified as different species ...
Takahiro Maeki, Yasuko Mori
doaj   +1 more source

The S‐Phase Arrest of Host Cells Caused by an Alpha‐Herpesvirus Genome Replication Facilitates Viral Recruitment of RNA Polymerase II to Transcribe Viral Genes

Cell Proliferation, EarlyView.
Viral infection arrests host cells in the S phase, which promotes vDNA synthesis and vRC formation, further facilitating viral recruitment of RNA Pol II to preferentially transcribe viral genes. ABSTRACT Herpesviruses rely on host RNA polymerae II (RNA Pol II) for their mRNA transcription, yet the mechanisms of which has been poorly defined, while ...
Qiqi Yang, Ying Wu, Mingshu Wang, Shun Chen, Renyong Jia, Qiao Yang, Dekang Zhu, Mafeng Liu, Xinxin Zhao, Shaqiu Zhang, Juan Huang, Xumin Ou, Di Sun, Bin Tian, Yu He, Zhen Wu, Anchun Cheng   +16 more
wiley   +1 more source