Results 111 to 120 of about 25,174,420 (247)

Shotgun Metagenomic Analysis Reveals Taxonomic and Functional Transitions in the Salivary Microbiome During Periodontal Disease Progression

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To characterise multi‐kingdom salivary microbiome profiles across clinically defined periodontal states and identify stage‐specific taxonomic and functional alterations using shotgun metagenomic sequencing. Materials and Methods In this cross‐sectional study, 204 adults (mean age 40.3 ± 7.6 years) from the SECRETO study (NCT01934725 ...
Muhammed Manzoor, Jaakko Leskelä, Eija Könönen, Leo Lahti, Jukka Putaala, Pirkko J. Pussinen, Susanna Paju   +6 more
wiley   +1 more source

Gammaherpesvirus infection modulates the temporal and spatial expression of SCGB1A1 (CCSP) and BPIFA1 (SPLUNC1) in the respiratory tract [PDF]

, 2014
This work was supported by a Royal Society (London) University Research Fellowship (to JPS), by Biotechnology and Biological Sciences Research Council (UK) grants BB/K009664/1 (to JPS, AK, and GHL) and BB/K009737/1 (CDB and LB), US Public Health Service ...
Leeming, G H, Moyo, NA, Bingle, Colin D, Bigley, A.L., Tripp, Ralph A, Bennett, E., Hughes, D J, Leeming, G.H., Moyo, N A, Bingle, L, Bigley, AL, Sample, JT, Bigley, Alison L, Bigley, A L, Tripp, R A, Sample, J T, Kipar, A, Moyo, Nathifa A, Stewart, JP, Stewart, J.P., Bennett, E, Tripp, R.A., Hughes, DJ, Kipar, A., Tripp, RA, Stewart, James P, Bingle, Lynne, Bennett, Elaine, Hughes, D.J., Leeming, Gail H, Sample, Jeffery T, Bingle, C D, Leeming, GH, Moyo, N.A., Sample, J.T., Moyo, Nathifa, Hughes, David J, Kipar, Anja, Bingle, CD, Bingle, L., Bingle, C.D., Stewart, J P   +41 more
core   +1 more source

Microbiome and Pathobiome Characterization in Farmed Barramundi (Lates calcarifer) During and Post Scale Drop Disease Outbreaks

Journal of Fish Diseases, EarlyView.
ABSTRACT Large‐scale double‐digest RAD sequencing (ddRADseq) datasets generated for genotyping are increasingly available in aquaculture, yet their unmapped reads remain largely unexplored for pathogen surveillance. Here, we evaluated the utility and limitations of repurposing unmapped ddRADseq reads to examine pathogen‐associated and disease ...
Nguyen Thanh Vu, Xueyan Shen, Susan Gibson‐Kueh, Maura Carrai, Celestine Terence, Zhi Weng Josiah Poon, Sarah Priyanka Nelson, Saengchan Senapin, Ha Thanh Dong, Jiun‐Yan Loh, Dean R. Jerry, Jose A. Domingos   +11 more
wiley   +1 more source

Viral MicroRNAs Repress the Cholesterol Pathway, and 25-Hydroxycholesterol Inhibits Infection

mBio, 2017
From various screens, we found that Kaposi’s sarcoma-associated herpesvirus (KSHV) viral microRNAs (miRNAs) target several enzymes in the mevalonate/cholesterol pathway.
Anna K. P. Serquiña, Diane M. Kambach, Ontara Sarker, Joseph M. Ziegelbauer   +3 more
doaj   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Viruses, Periodontitis, and Systemic Diseases

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the viral involvement in periodontitis and its relevance for systemic diseases. The oral cavity acts as an active viral reservoir and dissemination platform, where virus–microbiome interactions may promote dysbiosis, periodontitis progression, and systemic inflammatory effects, while the ...
Kim Natalie Solte, Yvonne L. Hernandez‐Kapila, Henrik Dommisch   +2 more
wiley   +1 more source

The incidence of vaccine‐associated sarcomas in cats: a systematic review and meta‐analysis

Journal of Small Animal Practice, EarlyView.
Objectives Feline injection‐site sarcoma is a rare but serious adverse event associated with vaccination in cats. Published estimates of feline injection‐site sarcoma incidence vary widely, contributing to uncertainty in clinical decision‐making and incidence communication.
F. Emdin, S. G. Naro, P. M. Hoang, K. A. Brown, N. Daneman, J. S. Weese   +5 more
wiley   +1 more source

Unveiling viral pathogens in acute respiratory disease: Insights from viral metagenomics in patients from the State of Alagoas, Brazil.

PLoS Neglected Tropical Diseases
BackgroundRespiratory illness affects individuals across all age demographics on a global scale, often precipitated by viral infections. The symptomatic manifestations of these diseases bear clinical resemblance, complicating the accurate determination ...
Gabriel Montenegro de Campos, Hazerral de Oliveira Santos, Alex Ranieri Jerônimo Lima, Anderson Brandão Leite, Gabriela Ribeiro, Jardelina de Souza Todão Bernardino, Jean Phellipe Marques do Nascimento, Juliana Vanessa Cavalcante Souza, Loyze Paola Oliveira de Lima, Marlon Breno Zampieri Lima, Mykaella Andrade de Araújo, Marta Giovanetti, Esper Georges Kallas, Sandra Coccuzzo Sampaio, Maria Carolina Elias, Svetoslav Nanev Slavov   +15 more
doaj   +1 more source

Human Herpesvirus 8 Causes a Wide Spectrum of Disease in Liver Transplant Recipients and May be Donor Derived: Case Series and Systematic Review of an Emerging Challenge

Transplant Infectious Disease, EarlyView.
Among 135 cases of post‐liver transplant HHV8 disease (4 from NSW), presentations varied, and mortality was high (44%). Donor screening was rare, and donor‐derived infection was suspected in 33%. Survival improved with mTORi, reduced immunosuppression, chemotherapy, and, for non‐KS disease, donor screening. ABSTRACT Background Human herpesvirus 8 (HHV8)
Karen M. J. Waller, Sudarshan Arvind, Simone I. Strasser, Ken Liu, Geoff W. McCaughan, David G. Bowen, Madeleine Gill, Rebecca Davis, William Rawlinson, Sacha Stelzer‐Braid, Geoff Watson, Vinay Vanguru, Tina Marinelli   +12 more
wiley   +1 more source

Varicella-zoster virus seroprevalence among reproductive-age women in Iran: a meta-analysis and implications for targeted immunization

BMC Infectious Diseases
Background Primary varicella-zoster virus (VZV) infection during pregnancy poses significant risks to both mother and fetus, including congenital varicella syndrome (CVS) and serious maternal complications.
Morteza Pourahmad, Mohammad Javad Tarrahi, Mahnaz Momenzadeh, Kiana Shahzamani, Abdolreza Sotoodeh Jahromi, Ziba Farajzadegan, Somayeh Haghighipour, Behrooz Ataei, Fatemeh Nikokar, Nasim Kakavand   +9 more
doaj   +1 more source