Results 121 to 130 of about 636,801 (264)

Targeting of Prosurvival Pathways as Therapeutic Approaches against Primary Effusion Lymphomas: Past, Present, and Future [PDF]

, 2015
Constitutively activated prosurvival pathways render cancer cells addicted to their effects. Consequently they turn out to be the Achilles’ heels whose inhibition can be exploited in anticancer therapy.
CIRONE, Mara, FAGGIONI, Alberto, FARINA, Antonella, GONNELLA, ROBERTA, GRANATO, Marisa, SANTARELLI, Roberta, TRIVEDI, PANKAJ   +6 more
core   +4 more sources

The S‐Phase Arrest of Host Cells Caused by an Alpha‐Herpesvirus Genome Replication Facilitates Viral Recruitment of RNA Polymerase II to Transcribe Viral Genes

Cell Proliferation, EarlyView.
Viral infection arrests host cells in the S phase, which promotes vDNA synthesis and vRC formation, further facilitating viral recruitment of RNA Pol II to preferentially transcribe viral genes. ABSTRACT Herpesviruses rely on host RNA polymerae II (RNA Pol II) for their mRNA transcription, yet the mechanisms of which has been poorly defined, while ...
Qiqi Yang, Ying Wu, Mingshu Wang, Shun Chen, Renyong Jia, Qiao Yang, Dekang Zhu, Mafeng Liu, Xinxin Zhao, Shaqiu Zhang, Juan Huang, Xumin Ou, Di Sun, Bin Tian, Yu He, Zhen Wu, Anchun Cheng   +16 more
wiley   +1 more source

Elevated iNOS and 3′-nitrotyrosine in Kaposi's Sarcoma tumors and mouse model

Tumour Virus Research, 2023
Kaposi's Sarcoma (KS) is a heterogenous, multifocal vascular malignancy caused by the human herpesvirus 8 (HHV8), also known as Kaposi's Sarcoma-Associated Herpesvirus (KSHV). Here, we show that KS lesions express iNOS/NOS2 broadly throughout KS lesions,
Olga Vladimirova, Samantha Soldan, Chenhe Su, Andrew Kossenkov, Owen Ngalamika, For Yue Tso, John T. West, Charles Wood, Paul M. Lieberman   +8 more
doaj  

Organoid Models to Study Human Infectious Diseases

Cell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu, Dan Chen, Xinzhi Yang, Liuliu Yang, Yuling Han   +4 more
wiley   +1 more source

Hippuristanol Reduces the Viability of Primary Effusion Lymphoma Cells both in Vitro and in Vivo

Marine Drugs, 2013
Primary effusion lymphoma (PEL) caused by Kaposi’s sarcoma-associated herpesvirus (also known as human herpesvirus-8) shows serious lymphomatous effusion in body cavities.
Masachika Senba, Naoki Mori, Junichi Tanaka, Harutaka Katano, Chie Ishikawa   +4 more
doaj   +1 more source

Additional file 3 of Association between human herpesvirus infection and cervical carcinoma: a systematic review and meta-analysis

Supplementary Material ...
Zhang, Han, Cai, Shunli, Xia, Yuan, Lin, Yangxuan, Zhou, Guozhong, Yu, Yinghui, Feng, Min   +6 more
openaire   +1 more source

Estudio genómico de cepas argentinas de Herpesvirus equino 1 [PDF]

, 2011
La infección por Herpesvirus equino 1 (EHV-1) tiene un significativo impacto económico en la producción equina mundial al causar abortos, enfermedad respiratoria, muertes perinatales y desórdenes neurológicos.
Eöry, Matías Leonel, Fuentealba, Nadia Analia, Galosi, Cecilia Monica, Pecoraro, Marcelo Ricardo, Sguazza, Guillermo Hernán, Valera, Alejandro Rafael   +5 more
core   +2 more sources

Torque teno virus as a marker of immune status in immunocompromised patients: A systematic review

European Journal of Clinical Investigation, EarlyView.
Abstract Background Torque teno virus (TTV) is not known to cause disease in humans; however, chronic inflammatory conditions and immunosuppression states can favour TTV replication. This study aimed to verify the effectiveness of TTV as an immune biomarker.
Janaina B. Medina, Fábio França Vieira e Silva, Rafael Antônio Velôso Caixeta, Bruna de Oliveira Rech, Alba Perez‐Jardón, María Elena Padín‐Iruegas, Mario Pérez‐Sayáns, Paulo Henrique Braz‐Silva, Karem L. Ortega   +8 more
wiley   +1 more source

Peri‐anaesthetic complications in 1798 equids undergoing high‐field elective orthopaedic MRI at a tertiary referral hospital

Equine Veterinary Journal, Volume 57, Issue 3, Page 666-673, May 2025.
Abstract Background Antimicrobial prophylaxis for elective orthopaedic magnetic resonance imaging (MRI) in equids is a topic of debate among practitioners and can have negative detrimental effects on patients if used unnecessarily. Objectives To describe the complications with elective orthopaedic MRI of horses, mules, and donkeys under general ...
Heath Manning, Sarah Sampson
wiley   +1 more source

Revenue Prediction of Local Event using Mathematical Model of Hit Phenomena [PDF]

arXiv, 2011
Theoretical approach to investigate human-human interaction in society performed using a many-body theory including human-human interaction. The advertisement is treated as an external force. The word of mouth (WOM) effect is included as a two-body interaction between humans. The rumor effect is included as a three-body interaction between humans.
arxiv