Human Herpesvirus 6A Induces Dendritic Cell Death and HMGB1 Release without Virus Replication
Human herpesvirus 6A (HHV-6A) is a common virus that has important immunomodulatory effects. Dendritic cells (DC) are key players in innate and adaptive immunity and are implicated in the pathogenesis of many human diseases, including infections.
Rasmus Gustafsson
doaj +1 more source
Human-robot co-manipulation of extended objects: Data-driven models and control from analysis of human-human dyads [PDF]
Human teams are able to easily perform collaborative manipulation tasks. However, for a robot and human to simultaneously manipulate an extended object is a difficult task using existing methods from the literature. Our approach in this paper is to use data from human-human dyad experiments to determine motion intent which we use for a physical human ...
arxiv
Expert Perspective: Diagnosis and Treatment of Castleman Disease
Summary Castleman disease (CD) is a major diagnostic challenge for Rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y.C. Chen+2 more
wiley +1 more source
Further strategies for evaluating the etiological role of a tumor-associated herpesvirus in marine turtle fibropapillomatosis [PDF]
In 1992, an interdisciplinary research team headquartered at the University of Florida began studies in key targeted areas of fibropapillomatosis (FP) etiology and pathogenesis.
Jacobson, Elliott, Klein, Paul A.
core
Rare Infectious Diseases: Detection and Clinical Implications
Rare infectious diseases are infections that are uncommon, have a low incidence, and are caused by newly emerging pathogens, cross‐species or ectopic infections, or host immunodeficiencies. The detection and diagnosis of rare infections is one of the main reasons for misdiagnosis and missed diagnosis.
Xin Qian+7 more
wiley +1 more source
Neural Free-Viewpoint Performance Rendering under Complex Human-object Interactions [PDF]
4D reconstruction of human-object interaction is critical for immersive VR/AR experience and human activity understanding. Recent advances still fail to recover fine geometry and texture results from sparse RGB inputs, especially under challenging human-object interactions scenarios.
arxiv
On the Effect of Information Asymmetry in Human-AI Teams [PDF]
Over the last years, the rising capabilities of artificial intelligence (AI) have improved human decision-making in many application areas. Teaming between AI and humans may even lead to complementary team performance (CTP), i.e., a level of performance beyond the ones that can be reached by AI or humans individually.
arxiv
Rainbow Kaposi's Sarcoma-Associated Herpesvirus Revealed Heterogenic Replication with Dynamic Gene Expression. [PDF]
Molecular mechanisms of Kaposi's sarcoma-associated herpesvirus (KSHV) reactivation have been studied primarily by measuring the total or average activity of an infected cell population, which often consists of a mixture of both nonresponding and ...
Campbell, Mel+10 more
core
Mapping protein–protein interactions by mass spectrometry
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu+4 more
wiley +1 more source
Nonprofessional Phagocytosis Can Facilitate Herpesvirus Entry into Ocular Cells
Phagocytosis is a major mechanism by which the mediators of innate immunity thwart microbial infections. Here we demonstrate that human herpesviruses may have evolved a common mechanism to exploit a phagocytosis-like entrapment to gain entry into ocular ...
Vaibhav Tiwari, Deepak Shukla
doaj +1 more source