Results 91 to 100 of about 187,276 (226)

Epstein‐Barr Virus Expressed Long Non‐Coding RNA (lncBARTs) Regulate EBV Latent Genome Replication

Advanced Science, Volume 13, Issue 8, 9 February 2026.
EBV produces abundant level of lncBARTs, which are essential for maintaining viral genome replication in EBV‐associated cancers. LncBARTs interact with a complex comprising BRD4, CTCF and viral protein EBNA1 at EBV oriP region. This interaction tethers oriP to host chromosomes, facilitating EBV episome replication.
Jiayan Liu, Dittman Lai‐Shun Chung, Larry Ka‐Yue Chow, Shuo Han, Wenkai Yi, Conor J. Cremin, Yingyin Liao, Pui Wang, Bobo Wing‐Yee Mok, Mingfang Ji, Jian Yan, Wei Dai, Honglin Chen   +12 more
wiley   +1 more source

Bovine Herpesvirus-4-Based Vector Delivering Peste des Petits Ruminants Virus Hemagglutinin ORF Induces both Neutralizing Antibodies and Cytotoxic T Cell Responses

Frontiers in Immunology, 2018
Peste des Petits Ruminants Virus (PPRV) is an extremely infective morbillivirus that primarily affects goats and sheep. In underdeveloped countries where livestock are the main economical resource, PPRV causes considerable economic losses.
Francesca Macchi, José Manuel Rojas, Andrea Elizabeth Verna, Noemí Sevilla, Valentina Franceschi, Giulia Tebaldi, Sandro Cavirani, Verónica Martín, Gaetano Donofrio   +8 more
doaj   +1 more source

Deregulation of HDAC5 by Viral Interferon Regulatory Factor 3 Plays an Essential Role in Kaposi's Sarcoma-Associated Herpesvirus-Induced Lymphangiogenesis. [PDF]

, 2018
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent for Kaposi's sarcoma (KS), which is one of the most common HIV-associated neoplasms.
Fan Li, Grace M. Aldrovandi, Hye Ryun Yu, Hye-Ra Lee, Jae U. Jung, Peter Palese, Pinghui Feng, Shou-Jiang Gao, Un Yung Choi, Young-Kwon Hong   +9 more
core   +3 more sources

Efficacy, Safety and Biological Characteristics of Formulation Based on Essential Oil Against Co‐Infections of Herpes Simplex Virus‐1 and Candida albicans

MicrobiologyOpen, Volume 15, Issue 1, February 2026.
Essential oils with anti‐HSV‐1 activity were identified through literature review and tested against Candida to develop a formulation for co‐infections. The blend was assessed for anti‐inflammatory properties, allergenic potential via standardized BAT, and overall antiviral efficacy.
Maura Di Vito, Domiziana Coggiatti, Marilena La Sorda, Stefania Garzoli, Giulia Lombardini, Debora Talamonti, Scilla Pizzarelli, Abdesselam Zhiri, Margherita Cacaci, Riccardo Torelli, Maurizio Sanguinetti, Francesca Bugli   +11 more
wiley   +1 more source

Establishment of a Bovine Herpesvirus 4 based vector expressing a secreted form of the Bovine Viral Diarrhoea Virus structural glycoprotein E2 for immunization purposes

BMC Biotechnology, 2007
Background The biological characteristics of BoHV-4 make it a good candidate as a gene delivery vector for vaccination purposes. These characteristics include little or no pathogenicity, unlikely oncogenicity, the capability to accommodate large amounts ...
Donofrio Gaetano, Sartori Chiara, Ravanetti Lara, Cavirani Sandro, Gillet Laurent, Vanderplasschen Alain, Taddei Simone, Flammini Cesidio   +7 more
doaj   +1 more source

Progress in RNA‐Targeted Therapeutics for Human Diseases

MedComm, Volume 7, Issue 2, February 2026.
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang, Aimin Jiang, Bin‐Kui Jia, Yuming Jin, Yinghu Chen, Zhaoyu Li, Yan Liao, Haoling Zhang, Zhiheng Lin, Xiao Fang, Linhui Wang   +10 more
wiley   +1 more source

The Involvement of Histone H3 Acetylation in Bovine Herpesvirus 1 Replication in MDBK Cells

Viruses, 2018
During bovine herpesvirus 1 (BoHV-1) productive infection in cell cultures, partial of intranuclear viral DNA is present in nucleosomes, and viral protein VP22 associates with histones and decreases histone H4 acetylation, indicating the involvement of ...
Liqian Zhu, Xinyi Jiang, Xiaotian Fu, Yanhua Qi, Guoqiang Zhu   +4 more
doaj   +1 more source

Detection of a novel gammaherpesvirus (genus Rhadinovirus) in wild muntjac deer in Northern Ireland [PDF]

, 2017
This study represents the initial part of an investigation into the potential for non-native, wild, free-living muntjac deer (Muntiacus reevesi) to carry viruses that could be a threat to livestock.
A Barlow, AI Ward, AJ Davison, Cheryl Ball, DR VanDevanter, E Cesarman, G Donofrio, GC Russell, Jaimie T. A. Dick, John McKillen, JTA Dick, K Tamura, K Yokoi, Kayleigh Hogg, Lisa Collins, M Kearse, MS Freeman, Neil Reid, Paula Lagan, RJ Putmam, RJ Putman, SF Altschul, Simon Doherty, T Passler, W Glawischnig   +24 more
core   +1 more source

Statistical properties of thermodynamically predicted RNA secondary structures in viral genomes

, 2008
By performing a comprehensive study on 1832 segments of 1212 complete genomes of viruses, we show that in viral genomes the hairpin structures of thermodynamically predicted RNA secondary structures are more abundant than expected under a simple random ...
A. Tuplin, C. Thurner, D.S.H. Chew, F. Lillo, F. Lillo, F. Lillo, F. Ratcliff, G.P. Schroth, H.O. Smith, J.S. Mattick, M. Spanò, M. Spanò, M.Y. Leung, P. Rice, P. Simmonds, P.E. Warburton, R. Cox, R. N. Mantegna, R.C. Lee, S. Miccichè, S.R. Eddy   +20 more
core   +1 more source

Prevalence of BoHV-1 seropositive and BVD virus positive bulls on Irish dairy farms and associations between bull purchase and herd status [PDF]

, 2015
peer-reviewedBackground BVD and IBR are contagious viral diseases highly prevalent in Irish cattle. Despite their significant reproductive and economic impact very little is known about the BVD and IBR status of stock bulls (a bull used ...
Martinez-Ibeas, Ana M, McClure, Jennifer, Power, C., Sayers, Riona   +3 more
core   +2 more sources