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Persistent infection of bovine herpesvirus type 4 in bovine endothelial cell cultures

Veterinary Microbiology, 1999
Herpesviruses can establish a persistent infection in the cells and tissues of their natural hosts and thus may produce diseases due to cytolytic infections. We have isolated a herpesvirus from a bovine vascular endothelial cell culture after continuous subculturing.
T M, Lin   +6 more
openaire   +2 more sources

Susceptibility of endothelial cells to bovine herpesvirus type 4 (BHV-4)

Journal of Virological Methods, 1997
The sensitivity of two different types of cells to bovine herpesvirus type 4 (BHV-4) was compared by median tissue culture infectious dose (TCID50) assays. The bovine arterial endothelial (BAE) cell culture derived from bovine carotid arteries was 100-1000 times more sensitive to two strains of BHV-4, Movar 33/63 and DN 599, than Madin Darby bovine ...
T M, Lin   +5 more
openaire   +2 more sources

Bovine herpesvirus 4 isolates: a comparison of three major glycoproteins

Veterinary Microbiology, 1991
Twenty-four Belgian field isolates of bovine herpesvirus 4 (BHV-4), together with four reference strains were compared by radio-immunoprecipitation and western blotting using a polyvalent antiserum and monoclonal antibodies raised against major glycoproteins.
Dubuisson, J.   +4 more
openaire   +2 more sources

Bovine herpesvirus 4 immediate early 2 (Rta) gene is an essential gene and is duplicated in bovine herpesvirus 4 isolate U

Veterinary Microbiology, 2011
The ORF50/Rta gene has been shown to be an essential gene for many gammaherpesviruses. Although the BoHV-4 ORF50/Rta homolog, immediate early gene 2 (IE2), has been shown to activate several BoHV-4 early and late promoters in cotransfection assays, there is no direct proof of its indispensability for progression of the virus to the lytic replication ...
Franceschi, V.   +7 more
openaire   +4 more sources

Bovine herpesvirus 4 (Movar herpesvirus)

1997
Presents the results of an expert evaluation of the carcinogenic risk to humans posed by infection with two lymphotropic herpesviruses: Epstein-Barr virus and Kaposi's sarcoma herpesvirus/human herpesvirus 8, a new human herpesvirus detected in 1994 in Kaposi's sarcoma associated with AIDS.
Thiry, Etienne   +3 more
openaire   +1 more source

An investigation of the aetiological role of bovine herpesvirus 4 in bovine endometritis

The Veterinary Journal, 2008
Uteri from 31 infertile cattle were examined for the presence of bovine herpesvirus 4 (BoHV-4) by nested polymerase chain reaction (PCR). Samples were also tested for bacteria, including chlamydiae and Mycoplasma bovis. BoHV-4 was detected by PCR in 27/31 (87.1%) samples, but the presence and amount of viral DNA was not correlated with histological and
K, Fábián   +4 more
openaire   +2 more sources

Genetic relationships between bovine herpesvirus 4 and the gammaherpesviruses epstein-Barr virus and herpesvirus saimiri

Virology, 1992
The overall arrangement of genes in the unique central part of the bovine herpesvirus type 4 (BHV-4) genome has been deduced by analysis of short DNA sequences. Twenty-three genes conserved in at least one of the completely sequenced herpesviruses have been identified and localized. All of these genes encoded amino acid sequences with higher similarity
Bublot, M.   +7 more
openaire   +2 more sources

Detection of bovine herpesvirus 4 DNA in aborted bovine fetuses.

Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 2007
The presence of Bovine herpesvirus 4 (BoHV-4) was investigated by several methods in 24 aborted bovine fetuses. Polymerase chain reaction (PCR) and in situ DNA hybridization proved the presence of BoHV-4 DNA in 7 (29%) of the fetuses. The BoHV-4 genome was detected in the cytoplasm of splenic lymphocytes and monocytes, and sometimes in renal tubular ...
Zoltán, Deim   +2 more
openaire   +1 more source

The biology of bovine herpesvirus-4 infection of cattle.

DTW. Deutsche tierarztliche Wochenschrift, 1990
The biology of bovine herpesvirus-4 (BHV-4) infection of cattle is reviewed. The infection is distributed worldwide. Most of isolated viruses are non-pathogenic in cattle; some of them are able to produce a genital disease. Twenty-nine structural polypeptides were described; ten of them are glycosylated.
Thiry, Etienne   +4 more
openaire   +2 more sources

Potential of bovine herpesvirus 4 as a gene delivery vector

Journal of Virological Methods, 2002
A cloning system was developed for construction of BHV-4 recombinants and recombinant virus BHV-4EGFPDeltaTK containing an enhanced green fluorescent protein (EGFP) gene was constructed. The host range of BHV-4EGFPDeltaTK was characterized in vitro.
DONOFRIO, Gaetano   +3 more
openaire   +3 more sources

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