Results 51 to 60 of about 2,202,173 (218)

Perturbation of lytic and latent gammaherpesvirus infection in the absence of the inhibitory receptor CEACAM1. [PDF]

, 2009
Control of gammaherpesvirus infections requires a complex, well orchestrated immune response regulated by positive and negative co-signaling molecules.
Kammerer Robert, Zimmermann, Wolfgang, Adler, Heiko, Guggemoos Simone, El-Gogo, Susanne, El-Gogo, S., Nicole Beauchemin, Beauchemin, Nicole, Heiko Adler, Beauchemin, N., Robert Kammerer, Kammerer, Robert, Kammerer, R., Beauchemin Nicole, Wolfgang Zimmermann, Susanne El-Gogo, Guggemoos, S., Guggemoos, Simone, Adler Heiko, Zimmermann Wolfgang, Zimmermann, W., Adler, H., El-Gogo Susanne, Simone Guggemoos   +23 more
core   +2 more sources

Long Non-Coding RNAs: Novel Players in Regulation of Immune Response Upon Herpesvirus Infection

Frontiers in Immunology, 2018
Herpesviruses have developed a variety of sophisticated immune evasion strategies to establish lifelong latent infection, including the use of long non-coding RNAs (lncRNAs).
Waqas Ahmed, Waqas Ahmed, Zheng-Fei Liu, Zheng-Fei Liu   +3 more
doaj   +1 more source

Epidemiological Survey and Genomic Insights Into Ostreid Herpesvirus 1 Transmission in the Blood Clam Anadara broughtonii in China (2019–2025)

Animal Research and One Health, EarlyView.
Seven‐year surveillance reveals a cold‐adapted OsHV‐1 lineage in blood clams, with disease onset at 13°C—3–5°C lower than in oysters—and identifies asymptomatic carriers and facility effluent as key transmission routes. ABSTRACT Ostreid herpesvirus 1 (OsHV‐1) poses a major threat to bivalve aquaculture, but its impact on blood clams (Anadara ...
Xiang Zhang, Bowen Huang, Tao Yu, Jingli Wang, Maole Wei, Huigang Kang, Chongming Wang, Changming Bai   +7 more
wiley   +1 more source

Gene expression studies of lytic infection and chromosomal integration of human herpesvirus 6. [PDF]

, 2008
Human herpesvirus 6 (HHV-6) was discovered in 1986 in patients with lymphoproliferative diseases and it has a predominant tropism for CD4+ T cells in vitro and in vivo.
Tsao, E.H.F.
core  

A beta-herpesvirus with fluorescent capsids to study transport in living cells. [PDF]

, 2012
Fluorescent tagging of viral particles by genetic means enables the study of virus dynamics in living cells. However, the study of beta-herpesvirus entry and morphogenesis by this method is currently limited.
Lisa Marcinowski, Marcinowski, Lisa, Ulrich H Koszinowski, Christophe Jung (152124), Jens von Einem, Gaul, Ulrike, Paul Walther, Einem, Jens von, Jens B Bosse, Paul Walther (113867), Ruzsics, Zsolt, Ulrike Gaul, Ulrich H. Koszinowski (152143), Bosse, Jens B., Zsolt Ruzsics (75383), Leonhard Popilka (152101), Leonhard Popilka, Christophe Jung, Jens B. Bosse (138966), Lisa Marcinowski (138962), Jens B. Bosse, Martina Taeglich (152115), Rudolf Bauerfeind (152093), Taeglich, Martina, Koszinowski, Ulrich H., Hannah Striebinger, Zsolt Ruzsics, Ulrike Gaul (3154), Ulrich H. Koszinowski, Jung, Christophe, Hannah Striebinger (152128), Martina Taeglich, Jens von Einem (152134), Bauerfeind, Rudolf, Striebinger, Hannah, Rudolf Bauerfeind, Walther, Paul, Popilka, Leonhard   +37 more
core   +2 more sources

New Paradigms for the Study of Ocular Alphaherpesvirus Infections: Insights into the Use of Non-Traditional Host Model Systems

Viruses, 2017
Ocular herpesviruses, most notably human alphaherpesvirus 1 (HSV-1), canid alphaherpesvirus 1 (CHV-1) and felid alphaherpesvirus 1 (FHV-1), infect and cause severe disease that may lead to blindness.
Matthew R. Pennington, Eric C. Ledbetter, Gerlinde R. Van de Walle   +2 more
doaj   +1 more source

What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?

Biotechnology and Bioengineering, EarlyView.
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady, Nicholas Donohue, Alexandra Bogdanovic, Sharon Davin, Brian Glennon, Niall Barron, C. Mark Smales   +6 more
wiley   +1 more source

Cytomegalovirus microRNAs facilitate persistent virus infection in salivary glands. [PDF]

, 2010
Micro (mi)RNAs are small non-coding RNAs that regulate the expression of their targets' messenger RNAs through both translational inhibition and regulation of target RNA stability.
Marcinowski, Lisa, Lars Dölken, Astrid Krmpotic, Jonjic, S. (Stipan), Kothe, Sheila, Ruzsics, Zsolt, Tanguy Mélanie, Koszinowski, Ulrich H, Dölken Lars, Krmpotic Astrid, Zsolt Ruzsics, Ruzsics, Z. (Zsolt), Tuddenham, L. (Lee), Jonjic Stipan, Elefant, N. (Naama), Tanguy, Mélanie, Elefant Naama, Pfeffer, S. (Sebastien), Koszinowski, U. (Ulrich H), Marcinowski Lisa, Lisa Marcinowski, Elefant, Naama, Ulrich H Koszinowski, Tuddenham Lee, Altuvia, Yael, Koszinowski Ulrich H., Lee Tuddenham, Stipan Jonjic, Pfeffer Sébastien, Altuvia, Y. (Yael), Kothe Sheila, Sébastien Pfeffer, Tuddenham, Lee, Mélanie Tanguy, Margalit, Hanah, Ruzsics Zsolt, Margalit Hanah, Marcinowski, L. (Lisa), Krmpotic, A. (Astrid), Koszinowski, Ulrich H., Dölken, L. (Lars), Tanguy, M. (Mélanie), Krmpotic, Astrid, Sheila Kothe, Dölken, Lars, Ulrich H. Koszinowski, Yael Altuvia, Naama Elefant, Pfeffer, Sébastien, Kothe, S. (Sheila), Hanah Margalit, Altuvia Yael, Jonjic, Stipan, Margalit, H. (Hanah)   +53 more
core   +1 more source

Post-exposure vaccination improves gammaherpesvirus neutralization.

PLoS ONE, 2007
Herpesvirus carriers transmit infection despite making virus-specific antibodies. Thus, their antibody responses are not necessarily optimal. An important question for infection control is whether vaccinating carriers might improve virus neutralization ...
Laurent Gillet, Janet S May, Philip G Stevenson   +2 more
doaj   +1 more source

Enhancing Adeno‐Associated Virus 2 Capsid Engineering Through Co‐Evolutionary Coupling

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated virus (AAV) has emerged as a leading platform for gene therapy. However, to unlock the full potential, their manufacturing yields, stability, and efficacy must all be improved. Rational design is limited by poor predictability and the potential impact of mutations on multiple important vector properties.
Sirimar Laosinwattana, Yiwen Li, Braulio Carrillo Sanchez, Ayesha Khan, Paul A. Dalby   +4 more
wiley   +1 more source