High-Risk Corneal Graft Rejection in the Setting of Previous Corneal Herpes Simplex Virus (HSV)-1 Infection [PDF]
Acknowledgments The authors thank M. Robertson and R. Fordyce for technical support during the duration of the study. The work performed in Aberdeen was supported by grant from Action Medical Research UK (SP4328; London, England, UK), NHS Grampian ...
Amescua, Guillermo +7 more
core +1 more source
Acute Herpetic Keratitis: What is the Role for Ganciclovir Ophthalmic Gel? [PDF]
Herpes simplex keratitis (HSK) is a major cause of corneal blindness in the world. Following the primary infection, the virus enters into a latent phase.
Hamrah, Pedram, Sahin, Afsun
core +3 more sources
Combined Treatment for Recurrent Herpetic Stromal Keratitis with Ulceration: a Case Report
Herpes simplex keratitis (HSK) is a severe ophthalmic pathology which comprises 20-50% of inflammatory diseases in the cornea. Since keratitis is characterized by a long-term duration, severity, and a tendency to recurrence, studies on ophthalmic herpes ...
L.F. Troychenko +2 more
doaj +1 more source
Pyrenocheata unguis-hominis: A new cause of fungal keratitis in a contact lens wearer
Purpose: Pyrenochaeta unguis-hominis (syn. Neocucurbitaria unguis-hominis) is a rare fungal species belonging to the Coelomycetes group, mostly isolated from infected nails and skin.We present a case of contact lens-related fungal keratitis caused by ...
Sima Nissan +3 more
doaj +1 more source
Phase 2 randomized, double-masked, vehicle-controlled trial of recombinant human nerve growth factor for neurotrophic keratitis [PDF]
Purpose: To evaluate the safety and efficacy of topical recombinant human nerve growth factor (rhNGF) for treating moderate-to-severe neurotrophic keratitis (NK), a rare degenerative corneal disease resulting from impaired corneal innervation.
Alio, Jorge +45 more
core +1 more source
Microbial Keratitis following Self-Retained Cryopreserved Amniotic Membrane
The aim of this study was to report a severe case of mixed fungal and bacterial microbial keratitis following implantation of a self-retained cryopreserved amniotic membrane, PROKERA® SLIM (Bio-Tissue, Inc) in a patient with history of neurotrophic ulcer
Rafah Fairaq +2 more
doaj +1 more source
Patiens and methods. We observed 111 patients with various forms of prolonged herpetic keratitis and inflammatory ENT pathology. All patients underwent a study of biological secretions (tear, saliva, blood and urine) for the presence of DNA of herpetic ...
G. M. Chernakova
doaj +1 more source
Bilateral herpetic keratitis. [PDF]
Thirty patients with bilateral herpetic keratitis were evaluated, 40% of whom were atopic. Stromal keratitis occurred in 40% of the eyes and recurrent ulceration in 68%. Four patients (5 eyes) developed secondary microbial keratitis. Visual acuity decreased to 6/60 or less because of corneal opacification in 17% of the eyes.
K R, Wilhelmus, M G, Falcon, B R, Jones
openaire +2 more sources
Phase I trial of recombinant human nerve growth factor for neurotrophic keratitis [PDF]
Neurotrophic keratitis/keratopathy (NK), a rare degenerative corneal disease, lacks effective pharmacologic therapies.1 Because NK pathology involves trigeminal nerve damage and loss of corneal innervation, nerve growth factor (NGF) is surmised to ...
Alio, Jorge +45 more
core +1 more source
Targeting Herpetic Keratitis by Gene Therapy
Ocular gene therapy is rapidly becoming a reality. By November 2012, approximately 28 clinical trials were approved to assess novel gene therapy agents.
Hossein Mostafa Elbadawy +4 more
doaj +1 more source

