Results 91 to 100 of about 27,678 (227)

Human‐derived cardiac‐neural microtissues reveal catecholaminergic polymorphic ventricular tachycardia is also a disease of the sympathetic neuron

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagram illustrating the proposed pathway in which regulatory defects might occur in sympathetic neurons derived from hiPSC in catecholaminergic polymorphic ventricular tachycardia (CPVT). Specifically, enhanced calcium transients appeared to derive from three sources: enhanced membrane excitability (due to loss of ...
Ni Li, Chenchen Zhang, Mengying Xu, YoonYoung Choi, Davi Sidarta‐Oliveira, Ruirui Dong, Xinyu Hu, Enrique M. Toledo, Cesar A. Prada‐Medina, Finbar Argus, Kun Liu, Mingyu Li, Linna Zhou, Hagan Bayley, Corey Smith, Chris Denning, Ana I. Domingos, Guoliang Hao, Dan Li, David J. Paterson   +19 more
wiley   +1 more source

Farmers' Preferences for Gene Editing Crops and Influencing Factors

Applied Economic Perspectives and Policy, Volume 48, Issue 5, Page 1481-1497, December 2026.
ABSTRACT Gene editing (GE) is gaining momentum worldwide, but limited data on UK farmers' preferences hinders our understanding of its potential impact amid deregulation debates. Based on a survey of 200 English arable farmers, we employ a Latent Class Analysis and Multinomial Logit regressions to investigate current preferences for GE crops.
Bertolozzi‐Caredio Daniele, Vigani Mauro   +1 more
wiley   +1 more source

Non‐rim‐enhancing intracranial abscess in a cat confirmed by MRI and histopathology

Journal of Small Animal Practice, EarlyView.
A. Vila Cabaleiro, S. Wyatt, H. G. Miller, E. Fitzgerald, G. O. Bertoldi, C. Llanos   +5 more
wiley   +1 more source

Being Wardable: Patient, Family and Staff Member Views of the Otherness of Critical Care Survivors in a Ward Setting

Journal of Clinical Nursing, Volume 35, Issue 12, Page 5653-5665, December 2026.
ABSTRACT Aims Discharge from an intensive care unit (ICU) to the ward has long been recognised as a difficult and dangerous time for patients. This study aims to explore the experiences of patients, family members and staff of ongoing care following discharge from ICU to the ward.
Sarah Vollam, Melanie Gager, Hilary Thomas, Peter Watkinson, Natalie Pattison   +4 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, Volume 20, Issue 11, Page 2876-2895, November 2026.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

The Impact of Iron‐Containing Particulate Matter on the Chemical Degradation of Cellulose Acetate in Collections

ChemPlusChem, Volume 91, Issue 11, November 2026.
Artificial particulate matter with high iron content and varied iron speciation accelerates cellulose acetate degradation, increasing chemical instability during aging. These findings identify a previously underexplored deterioration pathway and demonstrate that airborne pollutant composition can critically influence the preservation of historical ...
Francesca Azolini, Katherine Curran, Simoní Da Ros, Adam Gibson   +3 more
wiley   +1 more source

Healthcare Professionals’ Experiences of Barriers and Facilitators to ARFID Identification, Diagnosis and Treatment: A Rapid Review

European Eating Disorders Review, Volume 34, Issue 6, Page 1637-1647, November 2026.
ABSTRACT Objectives Despite increasing evidence of the physical and psychosocial impairments associated with Avoidant/Restrictive Food Intake Disorder (ARFID), there are currently no national guidelines for its assessment and treatment. In the absence of such guidance, it is crucial to understand the experiences of healthcare professionals (HCPs ...
Sandra‐Eve Bamigbade, Freya Cooper, Amanda Ludlow   +2 more
wiley   +1 more source

Young bodies, aging ovaries: A systematic review and meta‐synthesis of women's perspectives on spontaneous premature ovarian insufficiency

International Journal of Gynecology &Obstetrics, Volume 175, Issue 2, Page 619-630, November 2026.
Abstract Objectives Spontaneous premature ovarian insufficiency (POI) is a condition characterized by the cessation of ovarian function before age 40, unrelated to medical interventions. It affects approximately 3.5% of women worldwide and can result in significant emotional, physical, and social consequences.
Maria Patricia Roman, Shaurya Aggarwal, Stergios K. Doumouchtsis   +2 more
wiley   +1 more source

New Schmidt hammer exposure‐age dating calibrations for the Last Glacial Termination in NW Scotland: Development and application to undated Torridon Group sandstone surfaces in Wester Ross

Journal of Quaternary Science, Volume 41, Issue 8, Page 1326-1345, November 2026.
ABSTRACT An understanding of the terrestrial extent, retreat dynamics and climate–glacier coupling of ice masses during the Last Glacial Termination (LGT, ~18–11 ka) is often limited by a fragmentary geomorphological record and is dependent on precise, accurate and robust dating frameworks.
Alastair M. Curry, David Small, Oliver T. Bartlett, Jonathan Newitt   +3 more
wiley   +1 more source

Evaluation of quantitative accuracy in 4D DCE‐bCT: Insights from a perfusion phantom study

Medical Physics, Volume 53, Issue 11, November 2026.
Abstract Background Four‐dimensional dynamic contrast‐enhanced breast CT (4D DCE‐bCT) provides submillimeter spatial resolution and temporal sampling within seconds, offering potential for improved perfusion assessment in breast cancer. Its quantitative accuracy, however, must be validated.
Liselot C. Goris, Juan J. Pautasso, Koen Michielsen, Ioannis Sechopoulos   +3 more
wiley   +1 more source