Results 81 to 90 of about 27,678 (227)

Factors Associated With Challenging Behaviour in People With Severe‐Profound Intellectual Disabilities: A Systematic Review

open access: yesJournal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Individuals with severe to profound intellectual disability (ID) exhibit high support needs and significant communication impairments and may present with challenging behaviours such as aggression, self‐injury and stereotypies. These behaviours can cause distress, hinder healthcare access and delivery and impair quality of life for ...
I. D. C. van Balkom   +5 more
wiley   +1 more source

The addition of clotrimazole reduces but does not abrogate fungal dysbiosis during effective antibacterial therapy for canine otitis externa

open access: yesJournal of Small Animal Practice, EarlyView.
Objectives Malassezia dysbiosis commonly occurs after successful piperacillin‐tazobactam monotherapy for canine bacterial otitis externa. The study objective was to compare antimicrobial outcomes in dogs with otitis treated with piperacillin‐tazobactam in combination with the antifungal drug clotrimazole with a previous cohort treated with piperacillin‐
G. Gallow   +8 more
wiley   +1 more source

Exploiting New Opportunities to Deliver High Fibre in White Bread and Other Bakery Products

open access: yesNutrition Bulletin, EarlyView.
ABSTRACT Dietary fibre (DF) is essential for health, with higher levels of DF consumption being associated with reduced risk of cardiovascular diseases, type 2 diabetes and colorectal cancer. However, most UK consumers fall far below the recommended dietary intake of 30 g of DF a day for adults.
Peter R. Shewry   +16 more
wiley   +1 more source

The Heterogeneous Regional Employment Effects of Environmental Policies

open access: yesOxford Bulletin of Economics and Statistics, EarlyView.
ABSTRACT This paper examines the effects of Environmental Policies—measured by the OECD Environmental Policy Stringency Index (EPS)—on employment in 349 regions across 26 countries from 1990 to 2020. We find that more stringent EPS have short‐term negative effects on regional employment, which disappear in the medium term.
Luca Bettarelli   +4 more
wiley   +1 more source

Family Ties online help: Pilot evaluation of an online intervention to reduce the impact of parental conflict on children

open access: yesPsychology and Psychotherapy: Theory, Research and Practice, EarlyView.
Abstract Objectives Despite strong evidence indicating the adverse impact of parental conflict on child well‐being, the evidence base regarding effective intervention is generally poor and the needs of children impacted by parental conflict often go unaddressed.
Emma Morris   +4 more
wiley   +1 more source

Junior Doctor's Ideas, Concerns and Expectations About Electroconvulsive Therapy: An Educational Quality Improvement Project

open access: yesBJPsych Open
Aims There remains stigma surrounding electroconvulsive therapy (ECT) amongst junior doctors, as well as gaps in knowledge, recent studies have shown.
Victoria Selwyn   +3 more
doaj   +1 more source

From contamination to fever: The role of endotoxin levels in bacterially contaminated platelet concentrates

open access: yesVox Sanguinis, EarlyView.
Abstract Background and Objectives Growth of gram‐negative bacteria in a platelet concentrate (PC) is inevitably accompanied by the accumulation of endotoxin, which is the major component of the outer cell membrane of these organisms. However, less is known about the kinetics of endotoxin accumulation in PC and its biological activity.
Marcel Prax   +14 more
wiley   +1 more source

Evaluation of Ligand-Based Models on Opioids Receptors Form Street Emerged Hits

open access: yesEmerging Trends in Drugs, Addictions, and Health
The misuse of opioids has become a major public health crisis worldwide. Synthetic opioids, in particular, pose a significant danger due to their potency and potential for addiction.
V. Catalani   +3 more
doaj   +1 more source

A primary cell‐based fluidic co‐culture model to investigate drug transport across the human placenta

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of a flow‐driven in vitro model of the human placental barrier designed to study transport processes during pregnancy. The model recreates key features of the maternal–fetal interface, enabling the investigation of how nutrients and therapeutic compounds cross the placental barrier under physiologically ...
Barbara Fuenzalida   +7 more
wiley   +1 more source

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