Results 181 to 190 of about 87,019 (296)
Epigenetic reprogramming in multiple myeloma—Challenges and opportunities
International Journal of Cancer, Volume 158, Issue 2, Page 423-432, 15 January 2026.Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar +2 more
wiley +1 more source
The Heterochromatin protein 1 is a master regulator in RNA splicing precision deficient in ulcerative colitis [PDF]
, 2020 Jorge Mata-Garrido +17 more
openalex +1 more source
Comprehensive Mapping of Functional Enhancers in Chinese Hamster Ovary Cells
Biotechnology and Bioengineering, Volume 123, Issue 1, Page 196-211, January 2026.In this study, the authors identified regions with enhancer activity in the CHO cell genome using genome‐wide and targeted STARR‐seq. The analysis revealed thousands of newly identified enhancer sequences, where some of the most active sequences could drive transgene expression at levels similar to or higher than strong viral enhancers.
María Santos +9 more
wiley +1 more source
Heterochromatin protein 1 promotes self-renewal and triggers regenerative proliferation in adult stem cells [PDF]
, 2013 An Zeng +10 more
openalex +1 more source
Glia, Volume 74, Issue 1, January 2026.Astrocytic ATRX loss causes non‐cell‐autonomous neuronal hyperexcitability. Inducing ATRX deficiency in astrocytes causes selective long‐term memory deficits. Dynamic transcriptomic changes reveal metabolic and synaptic pathway dysregulation. ABSTRACT Astrocytes are increasingly recognized as active regulators of synaptic transmission and memory, yet ...
Miguel A. Pena‐Ortiz +6 more
wiley +1 more source
Diploid origins and early genome stabilization in the allotetraploid Arabidopsis suecica
New Phytologist, Volume 249, Issue 1, Page 524-538, January 2026.Summary Polyploidization, followed by genome downsizing, is a recurrent evolutionary cycle that dramatically reshapes genome structure. Newly formed polyploids must quickly adjust their cell division machinery to maintain stable chromosome inheritance, while long‐term stabilization involves rediploidization, returning the genome to a diploid‐like state.
Robin Burns +6 more
wiley +1 more source
Multiscale Analysis of Dynamics and Interactions of Heterochromatin Protein 1 by Fluorescence Fluctuation Microscopy [PDF]
, 2009 Katharina P. Müller +9 more
openalex +1 more source
Plant, Cell &Environment, Volume 49, Issue 1, Page 450-473, January 2026.ABSTRACT Glucosinolates (GSLs) are secondary metabolites central to plant defence in the Brassicaceae family. While the role of histone modifications in developmental gene regulation is well studied, their function in stress‐induced secondary metabolism remains unclear.
Dasom Choi +2 more
wiley +1 more source
Advanced Science, Volume 12, Issue 45, December 4, 2025.A novel chromatin‐labeling probe is developed to investigate chromatin mobility during differentiation. The silicon rhodamine–conjugated dCTP is efficiently delivered into iPSCs and NSCs using a synthetic transporter. Super‐resolution microscopy and single‐particle tracking show decreased chromatin mobility during differentiation.
Maruthi K. Pabba +11 more
wiley +1 more source