Journal of Microscopy, Volume 301, Issue 2, Page 168-186, February 2026.Abstract Malaria is one of the deadliest infectious diseases in the world, annually responsible for over 400,000 deaths. It is caused by parasites of the genus Plasmodium, which undergo remarkable structural changes during their development within different cells across various hosts.
Rachel Rachid +3 more
wiley +1 more source
Journal of Neurochemistry, Volume 170, Issue 2, February 2026.Ethanol exposure alters brain endothelial cell function and blood–brain barrier integrity. In human brain microcapillary endothelial cells (HBMEC) and mouse brain endothelial cells (MBEC) from a prenatal alcohol exposure (PAE) model, ethanol increased DNA methyltransferas‐1 (DNMT1) activity and reduced DNA methylation, affecting DNMT3a/3b, methyl‐CpG ...
Michele Siqueira +6 more
wiley +1 more source
The Plant Journal, Volume 125, Issue 3, February 2026.Significance Statement Contrary to expectation, NUPTs do not necessarily have a deleterious or ultimately neutral impact, nor are they necessarily purged from the genome. Instead, they can proliferate and eventually become fixed, generating new and novel genes, gene regions and regulatory elements, thereby significantly contributing to plant nuclear ...
Lorenzo Carretero‐Paulet +2 more
wiley +1 more source
Therapeutic targeting of chromatin alterations in leukemia and solid tumors
International Journal of Cancer, Volume 158, Issue 2, Page 382-408, 15 January 2026.Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner +7 more
wiley +1 more source
Epigenetic reprogramming in multiple myeloma—Challenges and opportunities
International Journal of Cancer, Volume 158, Issue 2, Page 423-432, 15 January 2026.Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar +2 more
wiley +1 more source
Revealing site-specific molecular features mediating contacts of heterochromatin protein 1 α (HP1α) and the interactions with chromatin and DNA in LLPS environments. [PDF]
Commun BiolZhai Z +13 more
europepmc +1 more source
Overlapping Roles in Chromosome Segregation for Heterochromatin Protein 1 (Swi6) and DDK in Schizosaccharomyces pombe. [PDF]
Genetics, 2019 Shen KF, Forsburg SL.
europepmc +1 more source
The Growth, Pathogenesis, and Secondary Metabolism of <i>Fusarium verticillioides</i> Are Epigenetically Modulated by Putative Heterochromatin Protein 1 (FvHP1). [PDF]
J Fungi (Basel)Jacquat AG +7 more
europepmc +1 more source
The Long-Sought-After Plant Heterochromatin Protein 1 [PDF]
Molecular Plant, 2019 openaire +1 more source
Heterochromatin protein 1 (HP1) of Schistosoma mansoni: non-canonical chromatin landscape and oviposition effects. [PDF]
Mem Inst Oswaldo Cruzda Trindade NS +7 more
europepmc +1 more source