Results 191 to 200 of about 87,019 (296)

Gene cloning, expression pattern analysis, and subcellular localization of LIKE HETEROCHROMATIN PROTEIN 1 (LHP1) homologs in chrysanthemum (Chrysanthemum morifolium Ramat.)

, 2019
Zhiping Wu, Yike Gao, Min Fan, Yaohui Gao   +3 more
openalex   +1 more source

UHRF1 Controls the Timing of RAD51 Removal During DNA Damage Repair Through Suppressing RFWD3

Advanced Science, Volume 12, Issue 45, December 4, 2025.
We demonstrate here that the recombinase RAD51 is protected by UHRF1 through ubiquitinating RFWD3, an E3 for RAD51, and this very process is inhibited by RAD51, leading to a triple negative feedback circuit that ensures appropriate levels of RFWD3 and RAD51 for DNA damage response. Abstract The RAD51 recombinase is evolutionarily conserved critical for
Guangxue Liu, Kaiyan Huang, Shiyao Liu, Ziyu Sheng, Pumin Zhang   +4 more
wiley   +1 more source

Nortriptyline Inhibits Lysosomal Exocytosis‐Mediated SASP During Gastric Cancer Progression via Targeting HOXA1‐PITX2 Phase Separation

Advanced Science, Volume 12, Issue 46, December 11, 2025.
This study identifies that HOXA1 facilitates transcriptional activity of PITX2 in liquid condensates, resulting in up‐regulation of MCOLN1 and RAB3A followed by lysosomal exocytosis of LGALS1 and IGFBP7 from senescent cells, thus activating AKT signaling and EMT.
Yi Zhou, Chunhui Yang, Xinyue Li, Xiaojing Wang, Wanju Jiao, Xiaolin Wang, Jiaying Qu, Bosen Zhao, Shunchen Zhou, Qiangsong Tong, Liduan Zheng   +10 more
wiley   +1 more source

Deletion of Elongator Protein 1 (Elp1) relieves heterochromatin defects in a Pol II mutant of Schizosaccharomyces pombe [PDF]

Mamta B Nirmal, C. Liu, Julia C. Finkel, Katherine S. Darrow, Tommy V. Vo   +4 more
openalex   +1 more source

Decrease in DNA methylation 1 interacts with chromomethylase and like heterochromatin protein 1 in Physcomitrella patens [PDF]

, 2019
Vimala Parihar, Meenakshi Dangwal, Deepshikha Arya, Sanjay Kapoor, Meenu Kapoor   +4 more
openalex   +1 more source

Preventing Neurons and Glial Cells Destruction in Substantia Nigra Pars Compacta and Striatum Using St. John's Wort and Stem Cells on Parkinson's Model

Brain and Behavior, Volume 15, Issue 12, December 2025.
‐ ABSTRACT Study Objective St. John's wort (Hypericum perforatum) has been used for centuries as a medicinal plant to remedy external disorders such as burns and wounds, as well as internal disorders such as nerve pain, anxiety, and depression. Bone marrow mesenchymal stem cells (BMSCs) are a heterogeneous population of pluripotent stromal cells that ...
Hamed Farzadmanesh, Hamidreza Sameni, Ali Ghanbari, Abbas Ali Vafaei, Ali Khaleghian, Majid Mirmohammadkhani, Laya Ghahari, Afsaneh Shokri, Manouchehr Safari   +8 more
wiley   +1 more source

A heterochromatin protein 1 (HP1) dimer and a proliferating cell nuclear antigen (PCNA) protein interact in vivo and are parts of a multiprotein complex involved in DNA replication and DNA repair [PDF]

, 2012
Dominika O. Trembecka-Lucas, Jurek Dobrucki   +1 more
openalex   +1 more source

The Aging Gut–Brain Axis: Effects of Dietary Polyphenols and Metal Exposure

Chronic Diseases and Translational Medicine, Volume 11, Issue 4, Page 251-268, December 2025.
The influence of gut microbiota on brain health ABSTRACT Diet provides essential metals, which are required for the growth, development, and well‐functioning of the body. Nonetheless, some natural and human activities add toxic heavy metals to the diet, consequently introducing them to our bodies, resulting in several disorders and death. The intestine,
Luqi Cao, Saurabh Kumar Jha, Neha Gupta, Xiang Chen, Renuka Soni, Luoxi Yuan, Rashi Srivastava, Zhe‐Sheng Chen   +7 more
wiley   +1 more source

Recruitment of Tat to Heterochromatin Protein HP1 via Interaction with CTIP2 Inhibits Human Immunodeficiency Virus Type 1 Replication in Microglial Cells

, 2003
Olivier Rohr, Dominique Lecestre, Sylvette Chasserot‐Golaz, Céline Marban, Dorina Avram, Dominique Aunis, Mark Leid, Evelyne Schaeffer   +7 more
openalex   +1 more source

Novel Drosophila Heterochromatin Protein 1 (HP1)/Origin Recognition Complex-associated Protein (HOAP) Repeat Motif in HP1/HOAP Interactions and Chromocenter Associations [PDF]

, 2003
RamaKrishna Badugu, Mohammed M. Shareef, Rebecca Kellum   +2 more
openalex   +1 more source