Results 201 to 210 of about 87,019 (296)

Epigenetic Regulation of Autophagy in Breast Cancer: Implications for Biomarker Discovery and Personalized Therapy

Cancer Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background Breast cancer remains one of the most common and lethal malignancies among women. Despite advanced targeted therapies and precision medicine, therapeutic resistance continues to undermine durable clinical responses. Increasing evidence links epigenetic dysregulation and autophagy as central contributors to breast cancer progression,
Bushra Faryal
wiley   +1 more source

Mapping and functional analysis of heterochromatin protein 1 phosphorylation in the malaria parasite Plasmodium falciparum. [PDF]

Sci Rep, 2019
Bui HTN, Niederwieser I, Bird MJ, Dai W, Brancucci NMB, Moes S, Jenoe P, Lucet IS, Doerig C, Voss TS.   +9 more
europepmc   +1 more source

Overlapping Roles in Chromosome Segregation for Heterochromatin Protein 1 (Swi6) and DDK in Schizosaccharomyces pombe. [PDF]

Genetics, 2019
Shen KF, Forsburg SL.
europepmc   +1 more source

Plasmodium falciparum Heterochromatin Protein 1 Marks Genomic Loci Linked to Phenotypic Variation of Exported Virulence Factors

, 2009
Christian Flueck, Richárd Bártfai, Jennifer Volz, Igor Niederwieser, Adriana M. Salcedo‐Amaya, Blaise Alako, Florian Ehlgen, Stuart A. Ralph, Alan F. Cowman, Zbynek Bozdech, Hendrik G. Stunnenberg, Till S. Voss   +11 more
openalex   +2 more sources

Relationship between Histone H3 Lysine 9 Methylation, Transcription Repression, and Heterochromatin Protein 1 Recruitment [PDF]

, 2005
M. Stewart, Jiwen Li, Jiemin Wong
openalex   +1 more source

Mechanical Signaling: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 6, Issue 12, December 2025.
In this review, we summarize cell–ECM interactions and delve into the complex mechanotransduction. We introduce advanced research methods and emerging clinical tools used to study cellular mechanical phenotypes, mechanotransduction, and disease progression. Additionally, we analyze the role of mechanical biomarkers in the development and progression of
Yicen Long, Peng Wang, Jiacheng Lei, Baihai Su, Qiang Wei, Xiaojing Liu   +5 more
wiley   +1 more source

The Growth, Pathogenesis, and Secondary Metabolism of <i>Fusarium verticillioides</i> Are Epigenetically Modulated by Putative Heterochromatin Protein 1 (FvHP1). [PDF]

J Fungi (Basel)
Jacquat AG, Podio NS, Cañizares MC, Velez PA, Theumer MG, Areco VA, Garcia-Pedrajas MD, Dambolena JS.   +7 more
europepmc   +1 more source

Alternative Splicing: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets

MedComm, Volume 6, Issue 12, December 2025.
Alternative splicing (AS) expands proteomic diversity and functional complexity in eukaryotes, regulated by spliceosomal components, RNA elements, and epigenetic modifications. Dysregulated AS contributes to diseases, including cancer, neurodegenerative disorders, and cardiovascular conditions, among others. Therapeutic interventions, such as antisense
Zhi‐Min Zhu, Xiao‐Mei Wu, Yan Hu, Xiao‐Lan Bian, Ya‐Qin Wang, Qiong‐Ni Zhu   +5 more
wiley   +1 more source

Heterochromatin protein 1 (HP1) of Schistosoma mansoni: non-canonical chromatin landscape and oviposition effects. [PDF]

Mem Inst Oswaldo Cruz
da Trindade NS, Valentini MB, Rognon A, Mendes TMF, Gomes MS, Allegretti SM, Grunau C, Cabral FJ.   +7 more
europepmc   +1 more source

Knockdown of heterochromatin protein 1 binding protein 3 recapitulates phenotypic, cellular, and molecular features of aging. [PDF]

Aging Cell, 2019
Neuner SM, Ding S, Kaczorowski CC.
europepmc   +1 more source