Results 221 to 230 of about 87,019 (296)

The Caenorhabditis elegans Ortholog of TDP-43 Regulates the Chromatin Localization of the Heterochromatin Protein 1 Homolog HPL-2. [PDF]

open access: yesMol Cell Biol, 2018
Saldi TK   +6 more
europepmc   +1 more source

Heterogeneity of Cellular Senescence: Subtype‐Specific Mechanisms and the Emerging Role of Plasma Membrane Damage

open access: yesCancer Science, Volume 116, Issue 12, Page 3274-3285, December 2025.
Just as the term “cancer cell” encompasses a wide spectrum of cells, the term “senescent cell” should also be regarded as an umbrella term that includes cells with heterogeneous molecular profiles. In this review, we provide an updated overview of the molecular mechanisms underlying distinct senescent cell subtypes induced by various stimuli, including
Enaam Alghamdi, Keiko Kono
wiley   +1 more source

BRD4 facilitates DNA damage response and represses CBX5/Heterochromatin protein 1 (HP1). [PDF]

open access: yesOncotarget, 2017
Pongas G   +9 more
europepmc   +1 more source

Overcoming BET‐inhibitor JQ1 resistance in aggressive non‐small cell lung cancer by inducing ferroptosis via inhibition of the BRD2–FTH1 axis

open access: yesThe FEBS Journal, Volume 292, Issue 23, Page 6345-6364, December 2025.
Recent studies emphasize alternative functions of FTH1 relevant for nuclear processes, such as transcriptional regulation. This study shows a novel FTH1/BRD2 association in non‐small cell lung carcinoma (NSCLC). This nuclear interaction affects BRD2 protein stability in aggressive NSCLC cells.
Stefania Scicchitano   +9 more
wiley   +1 more source

Establishment of transgenic Drosophila suzukii lines that express phiC31 integrase and carry the sepia gene as a marker for transformation

open access: yesInsect Molecular Biology, Volume 34, Issue 6, Page 960-969, December 2025.
Germline transformation of the Drosophila suzukii se1 strain with the wild‐type sepia gene (~1.8 kb) using a piggyBac vector. Most lines show full rescue of sepia mutant eye colour. The lines express phage phiC31 integrase in the germline using a Dsnanos promoter.
Kalindu Ramyasoma Hewawasam   +2 more
wiley   +1 more source

Heterochromatin Protein 1 Is Extensively Decorated with Histone Code-like Post-translational Modifications [PDF]

open access: hybrid, 2009
Gary LeRoy   +5 more
openalex   +1 more source

DNA methylation contributes to plant acclimation to naturally fluctuating light

open access: yesNew Phytologist, Volume 248, Issue 5, Page 2361-2375, December 2025.
Summary Plants in the natural environment experience continuous dynamic changes in light intensity. Here, we exposed Arabidopsis thaliana plants to naturally fluctuating light (FL) regimes alongside traditional square light (SQ) regimes such as those often found in control environment growth chambers.
Robyn A. Emmerson   +5 more
wiley   +1 more source

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