Results 61 to 70 of about 65,696 (224)
Nature Communications, 2020 Enriching the chemical space of polycyclic heterocycles is of high value in chemical biology. Here, the authors report an electrooxidative protocol for the regioselective dearomative annulation of indoles and benzofurans under undivided cell conditions ...
Kun Liu +9 more
doaj +1 more source
, 2015 Enantioselective Catalytic Reactions with N‑Acyliden Penta-atomic Aza-heterocycles.
Giuseppe Faita (1525096) +2 more
core +1 more source
Stereoselectively fluorinated N-heterocycles: a brief survey
Beilstein Journal of Organic Chemistry, 2013 The stereoselective incorporation of fluorine atoms into N-heterocycles can lead to dramatic changes in the molecules’ physical and chemical properties.
Xiang-Guo Hu, Luke Hunter
doaj +1 more source
Dual Nickel/Photoredox‐Catalyzed Regio‐ and Enantioselective Alkenylation of Epoxides
Advanced Science, EarlyView.Ni/photoredox‐catalyzed stereoconvergent cross‐electrophile coupling of racemic epoxides with alkenyl bromides is described, affording β‐alkenyl products with up to 95% ee, excellent E‐selectivity, and complete regiocontrol. These versatile intermediates enable diverse chiral synthons; mechanistic studies suggest a halide ring‐opening followed by ...
Hongyan Lan +4 more
wiley +1 more source
Recent Discovery of Nitrogen Heterocycles from Marine-Derived Aspergillus Species
Marine DrugsNitrogen heterocycles have drawn considerable attention because of their structurally novel and significant biological activities. Marine-derived fungi, especially the Aspergillus species, possess unique metabolic pathways to produce secondary ...
Jueying Shi +8 more
doaj +1 more source
Nature Communications, 2017 Fused N-heterocycles are structural motifs observed in natural products and bioactive compounds. Here, the authors developed divergent copper- and gold-catalyzed oxidative cyclizations of diynes to two types of tricyclic N-heterocycles and rationalized ...
Wen-Bo Shen +7 more
doaj +1 more source
Quantum‐Trained AI Enables Inverse Design of Organic Frontier Orbitals at Billion‐Scale
Advanced Science, EarlyView.Quantum‐trained AI links molecular substructures to frontier‐orbital energetics and enables interpretable screening across nearly one billion GDB‐13 molecules. By combining fragment‐ and ring‐level insights with donor–acceptor energy alignment against ITIC, the framework narrows an immense chemical space to a small set of promising candidates and ...
Yeongnam Ko, Se Jin Kim, Ki Chul Kim
wiley +1 more source
, 2018 Simple solid-state mixing and calcination of catalytic amounts of metal-organic frameworks (MOFs) in the presence of aluminosilicates allow for the generation of active and robust supported metal oxide nanoparticles that catalyze C–C and C–N bond ...
Dirk E. De Vos (1347948) +7 more
core +1 more source
Advanced Science, EarlyView.Time‐resolved synchrotron radiography reveals the internal evolution of electrochemical double‐layer capacitors under abusive overcharge. EDLCs are shown to follow a thermally driven failure pathway involving electrolyte decomposition, gas generation, and structural collapse, distinct from chemically driven thermal runaway effects of Lithium‐ion ...
Thomas Dore +19 more
wiley +1 more source