Lifestyle Factors Associated With Colorectal Adenomas: Results From a Vietnamese Case–Control Study
International Journal of Cancer, EarlyView.ABSTRACT Although colorectal cancer (CRC) is the fourth most common cancer in Vietnam, evidence on lifestyle factors associated with colorectal adenomas (CRA) remains limited. We conducted a case–control study to examine lifestyle factors associated with CRA.
Chi Thi‐Du Tran +6 more
wiley +1 more source
Metabolic effects of heterocyclic amines on insulin‑induced AKT phosphorylation and gluconeogenic gene expression are modified by N -acetyltransferase 2 genetic polymorphism. [PDF]
Pharmacogenet GenomicsWalls KM +4 more
europepmc +1 more source
Journal of Heterocyclic Chemistry, EarlyView.A robust method for synthesizing substituted oxadiazepines and related heterocycles via intramolecular SNAr is detailed. Under mild conditions, this methodology has been leveraged to afford products of varying electronic and aryl nature in up to 99% yields.
Matthew W. Reeves +4 more
wiley +1 more source
The inhibition effect and mechanism of typical hydrocolloids on the formation of heterocyclic amines: A study based on quantum chemical computation analysis. [PDF]
Curr Res Food SciHuang T +6 more
europepmc +1 more source
Journal of the Science of Food and Agriculture, EarlyView.Abstract Food processing generates substantial amounts of byproducts rich in valuable bioactive compounds, particularly polyphenols, known for their antioxidant, anti‐UV, and antimicrobial properties. These molecules hold great potential in sectors such as food, cosmetics, and pharmaceuticals.
Paul Sauvetes +2 more
wiley +1 more source
First report on a series of food-derived mutagenic and carcinogenic heterocyclic amines. [PDF]
Proc Jpn Acad Ser B Phys Biol SciTotsuka Y, Ochiai M, Wakabayashi K.
europepmc +1 more source
Senotherapeutics for Knee Osteoarthritis
Medicinal Research Reviews, EarlyView.ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman +6 more
wiley +1 more source
Investigation of the dose and structure effects of lipid oxidation products aldehydes on the generation of heterocyclic amines: A case study of 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine (PhIP). [PDF]
Food Chem XZhao M +7 more
europepmc +1 more source
Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies
Medicinal Research Reviews, EarlyView.ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva +23 more
wiley +1 more source