Results 41 to 50 of about 66,085 (162)

Stereoselective Synthesis of α-Amino-C-phosphinic Acids and Derivatives

Molecules, 2016
α-Amino-C-phosphinic acids and derivatives are an important group of compounds of synthetic and medicinal interest and particular attention has been dedicated to their stereoselective synthesis in recent years. Among these, phosphinic pseudopeptides have
José Luis Viveros-Ceballos, Mario Ordóñez, Francisco J. Sayago, Carlos Cativiela   +3 more
doaj   +1 more source

Meat and cancer: haemoglobin and haemin in a low calcium diet promote colorectal carcinogenesis at the aberrant crypt stage in rats [PDF]

, 2003
High intake of red meat, but not of white meat, is associated with an increased risk of colon cancer. However, red meat does not promote cancer in rodents.
Corpet, Denis E., Petit, Claude, Pierre, Fabrice, Taché, Sylviane, Van der Meer, Roleof   +4 more
core   +5 more sources

Copper-Catalyzed Asymmetric Carboboronation of Allenes to Access α-Quaternary Amino Esters with Adjacent Stereocenters

Cell Reports Physical Science, 2020
Summary: Optically active α-quaternary amino acids have received much attention because of the important biomedical applications implicated for compounds containing this structure.
Chao-Yang Zhao, Hao Zheng, Ding-Wei Ji, Xiang-Ting Min, Yan-Cheng Hu, Qing-An Chen   +5 more
doaj   +1 more source

Asymmetric Reduction of Lactam-based β-Aminoacrylates. Synthesis of Heterocyclic β2-Amino Acids [PDF]

, 2016
The ability to affect asymmetric reduction of heterocyclic β-aminoacrylates 1 (n = 1–3) has been assessed with pyrrolidine and piperidone variants generating the corresponding N-heterocyclic β2-amino acids 3b and 5b with high enantioselectivity (≥97% ee)
Gallagher, Timothy, Parker, Jeremy S., Perry, Matthew W D, Rego Campello, Hugo, Ryberg, Per   +4 more
core   +2 more sources

Gold amides as anticancer drugs: synthesis and activity studies [PDF]

, 2013
Modular gold amide chemotherapeutics: Access to modern chemotherapeutics with robust and flexible synthetic routes that are amenable to extensive customisation is a key requirement in drug synthesis and discovery.
Amagai, Amruta Shrikhande, Bjornstedt, Chen, Chris Gallop, Cox, Davis, Eddy M. E. Viseux, Eva Hoffmann, Fricker, Gabbiani, Helen Yong, Hickey, Hill, Lemke, Lima, Mariusz Bobin, Mark Roe, Mezailles, Modica-Napolitano, Omata, Orvig, Ott, Patra, Poole, Rebecca Gates, Shuvashri Chaudhuri, Sonya Newcombe, Stallings-Mann, Thaqi, Wetzel, Yan, Yannick Pace, Zhang, Zhang   +34 more
core   +1 more source

Beyond Peptides and Peptidomimetics: Natural Heteroaromatic Amino Acids in the Synthesis of Fused Heterocyclic Frameworks for Bioactive Agents

Organics
Heterocycle cores are widely used in medicinal chemistry for developing bioactive compounds. In this scenario, using cheap and accessible starting material to build these heterocycles is desirable to obtain new drug candidates for cost-efficient ...
Isis Apolo Silveira de Borba, Jamile Buligon Peripolli, Angélica Rocha Joaquim, Fernando Fumagalli   +3 more
doaj   +1 more source

N,N’-Substituted 1,2,5 Thiadiazolidine 1,1-Dioxides: Synthesis, Selected Chemical and Spectral Proprieties and Antimicrobial Evaluation â€

Molecules, 2005
The sulfamide functional group is increasingly relevant in both medicinal and bioorganic chemistry. We report here practical access to a series of N2,N5-substituted five-membered cyclosulfamides. The five-membered heterocyclic motif was prepared starting
N. Aouf, Z. Regainia, R. Djeribi, A. Bendjeddou   +3 more
doaj   +1 more source

Imidazopyrrolone/imide copolymers Patent [PDF]

, 1970
Synthesis and chemical properties of imidazopyrrolone/imide ...
Bell, V. L., Jr., Pezdirtz, G. F.
core   +1 more source

5,6-Dihydro-2H-pyran-3(4H)-on als Baustein zur Synthese pyrananellierter Heterocyclen [PDF]

, 1984
Während 5,6-Dihydro-2H-pyran-3(4H)-on (3) sich mit ortho-substituierten Phenylcarbonylverbindungen nur in Einzelfällen regioselektiv zu pyrananellierten Heterocyclen umsetzt - z. B.
Eiden, Fritz, Wanner, Klaus Th.
core   +1 more source

Formation of heterocyclic aromatic amines in model systems of sucrose, lactose, amino acids and creatine [PDF]

BIO Web of Conferences
The article presents experimental data on the study of heterocyclic aromatic amines formation in model matrices consisting of amino acids (8 essential, glutamic acid and aspartic acid), carbohydrates (sucrose, lactose) and creatine.
Utyanov Dmitry, Polishchuk Ekaterina, Kibitkina Anastasiya, Reshchikov Maksim   +3 more
doaj   +1 more source