International Journal of Electrochemical Science, 2020 In this work, different structures of amino acid-functionalized electrochemically reduced graphene oxide-modified glassy carbon electrodes (ERGO/GCEs) were developed and applied for the determination of nitrite. L-arginine (L-Arg), L-tyrosine (L-Tyr) and
Peilong Wang +4 more
doaj +1 more source
Expanding a fluorescent RNA alphabet: synthesis, photophysics and utility of isothiazole-derived purine nucleoside surrogates. [PDF]
, 2017 A series of emissive ribonucleoside purine mimics, all comprised of an isothiazolo[4,3-d]pyrimidine core, was prepared using a divergent pathway involving a key Thorpe-Ziegler cyclization.
Fin, Andrea +2 more
core +1 more source
Synthesis of extended fluorinated tripeptides based on the tetrahydropyridazine scaffold
Beilstein Journal of Organic ChemistryThe synthesis of tripeptides incorporating new fluorinated heterocyclic hydrazino acids, based on the tetrahydropyridazine scaffold is described. Starting from simple fluorinated hydrazones, these non-proteinogenic cyclic β-amino acids were easily ...
Thierry Milcent +3 more
doaj +1 more source
Chemical Deuteration of α-Amino Acids and Optical Resolution: Overview of Research Developments
BioengineeringDeuterium-labelled amino acids have found extensive applications in such research areas as pharmaceutical, bioanalytical, neutron diffraction, inelastic neutron scattering, in analysis of drug metabolism using mass spectrometry (MS), and, structuring of ...
Nageshwar R. Yepuri
doaj +1 more source
Mechanism and Application of Baker–Venkataraman O→C Acyl Migration Reactions [PDF]
, 2014 This literature review focuses on the O→C acyl migration of aryl esters to yield the corresponding 1,3-dicarbonyl products—a reaction known as the Baker–Venkataraman rearrangement—and outlines their subsequent transformations.
Ameen, Dana, Snape, Timothy James
core +1 more source
Risk assessment of chemical substances of safety concern generated in processed meats
Food Science and Human Wellness, 2019 This manuscript is reviewing the presence of substances of safety concern that may be generated in different types of meat products. Such substances include N-nitrosamines that can be generated under certain conditions when using nitrite as preservative,
Mónica Flores +3 more
doaj +1 more source
Доповiдi Нацiональної академiї наук УкраїниA simple preparative synthesis of the heterocyclic system tetrahydropyrido[3,4-c]pyridazine has been developed within the framework of the IEDDA reaction of sym-tetrazine with methyl 2-(tert-butoxycarbonylamino)pent-4-ynoate.
O.V. Svaljavin +3 more
doaj +1 more source
Strategies against nonsense: oxadiazoles as translational readthrough-inducing drugs (TRIDs) [PDF]
, 2019 This review focuses on the use of oxadiazoles as translational readthrough-inducing drugs (TRIDs) to rescue the functional full-length protein expression in mendelian genetic diseases caused by nonsense mutations.
Campofelice A. +6 more
core +1 more source
Influence of amino acids on the formation of mutagenic/carcinogenic heterocydic amines in a model system [PDF]
, 2017 Mixtures of creatinine, glucose and various single amino acids were heated at 180°C for 10 min in an aqueous model system. The heated mixtures all showed mutagenic activity, ranging from 80 to 2400 TA98 revertant colonies/μmol creatinine with metabolic ...
Fay, Laurent B. +4 more
core
Recent developments in the Suzuki-Miyaura reaction: 2010-2014 [PDF]
, 2015 The Suzuki-Miyaura reaction (SMR), involving the coupling of an organoboron reagent and an organic halide or pseudo-halide in the presence of a palladium or nickel catalyst and a base, has arguably become one of most utilized tools for the construction ...
Maluenda, Irene, Navarro, Oscar
core +2 more sources