Results 101 to 110 of about 468,328 (285)
Chemistry – A European Journal, EarlyView.A rapid and efficient protocol for the synthesis of 2‐benzylbenzaldehydes and anthracenes is reported, based on the infrared (IR) irradiation‐assisted Pd‐catalyzed C(sp3)─H arylation and the tandem C(sp3)─H arylation/electrophilic aromatic cyclization of ortho‐tolualdehydes with aryl iodides via a transient directing group (TGD) strategy.
Matteo Renato Martina +6 more
wiley +1 more source
Modulation of Epigenetic Control by Advanced Molecular Tweezers
Chemistry – A European Journal, EarlyView.Tailored dimeric molecular tweezers recognize the DNA‐binding part of Histone H4 and interrupt the essential histone‐DNA interaction. ABSTRACT This work addresses the question if supramolecular systems can be tailored to interfere with posttranslational modifications (PTM) and epigenetics.
My‐Hue‐Le +9 more
wiley +1 more source
Heterocyclic amines in poultry products: a literature review.
, 2002 Health risks associated with heterocyclic amines in cooked foods have been discussed and analysed since the presence of these food mutagens was first detected.
K. Skog +5 more
core +2 more sources
Heterocyclic Aromatic Amines and Risk of Kidney Stones: A Cross-Sectional Study in US Adults. [PDF]
Front Public Health, 2022 Zhang G, Zou X, Mao W, Chen M.
europepmc +1 more source
Electrochemical Cross-Dehydrogenative Aromatization Protocol for the Synthesis of Aromatic Amines
The introduction of amines onto aromatics without metal catalysts and chemical oxidants is synthetically challenging. Herein, we report the first example of an electrochemical cross-dehydrogenative aromatization (ECDA) reaction of saturated ...
Shao-Kun Tao (11983269) +9 more
core +1 more source
Highly functionalised fused heterocycle synthesis from fluoropyridines [PDF]
, 2006 Current approaches to drug discovery tends to involve the rapid analogue synthesis and testing of small, focused libraries of low molecular weight, structurally similar "drug-like" molecules, often based around heterocyclic core scaffolds.
Cartwright, Matthew William
core
Chemistry – A European Journal, EarlyView.Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi +6 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.Easily synthesized [Ge([12]crown‐4)2][OTf]2 catalyzes the hydrosilylation of aldehydes to give reductively coupled ethers via a carbonyl‐activated reaction pathway. The mechanism proceeds through two distinct steps: hydrosilylation followed by etherification. The open coordination face of the active cationic Ge(II) catalyst facilitates the coordination
Sarah L. McOnie +2 more
wiley +1 more source
The Use of Spices and Fruit as Marinades to Prevent and Reduce HAA (Heterocyclic Amines Aromatic) and PAH (Polycyclic Aromatic Hydrocarbons) Levels in Grilled or Fried Meat to Prevent Cancer [PDF]
Cancer is a deadly non-communicable disease, and one of the contributing factors to the increased risk of cancer is the consumption of carcinogenic compounds such as heterocyclic aromatic amines (HAAs) and polycyclic aromatic hydrocarbons (PAHs) during ...
Sitasari, Almira +3 more
core +1 more source
C‐Terminal Functionalization Methods of Amino Acids, Peptides, and Proteins
Chemistry – A European Journal, EarlyView.C‐terminal functionalization offers powerful routes to peptide and protein diversification, yet epimerization, hydrolysis, and selectivity remain key challenges. This Review surveys enzymatic, decarboxylative, and condensation strategies, highlighting advances toward chemo‐ and regioselective, protecting‐group‐free, atom‐efficient methods applicable to
Jay Hanssens +3 more
wiley +1 more source