Results 1 to 10 of about 92,883 (234)

Design and Synthesis of Structurally Modified Analogs of 24Z-Isomasticadienonic Acid with Enhanced Anti-Proliferative Activity [PDF]

open access: yesMolecules
Τriterpenic acids represent a prominent class of bioactive compounds, with a wide range of biological properties, including anti-inflammatory, antiviral, and anticancer effects. Among them, 24Z-isomasticadienonic acid (IMNA), a major constituent of Chios
Panagiota Stamou   +5 more
doaj   +2 more sources

Synthesis Characterization of Some New Heterocyclic Compounds Containing1, 3-Oxazepine Ring [PDF]

open access: yesKirkuk Journal of Science, 2016
تم تحضیر سلسلة من مشتقات 1, 3 - الاوکسازبین من خلال خطوتین الاول: یتضمن تحضیر مشتقات الایمین (A7-A1) من تفاعل 4 - هیدروکسی بنزالدیهاید مع امینات معوضة مختلفة وباستخدام حامض الخلیک الثلجی.
Jawdat H. Abdul – Wahid   +2 more
doaj   +1 more source

Exploration of Benzenesulfonamide-Bearing Imidazole Derivatives Activity in Triple-Negative Breast Cancer and Melanoma 2D and 3D Cell Cultures

open access: yesPharmaceuticals, 2021
Heterocyclic compounds are one of the main groups of organic compounds possessing wide range of applications in various areas of science and their derivatives are present in many bioactive structures. They display a wide variety of biological activities.
Benas Balandis   +2 more
doaj   +1 more source

Synthesis, Characterization, and Preliminary Evaluation of Antimicrobial activity of Imines derived from Vanillic Acid Conjugated to Heterocyclic

open access: yesIraqi Journal of Pharmaceutical Sciences, 2023
The purpose of this research is to prepare new vanillic acid derivatives with 1,2,4-triazole-3-thiol heterocyclic ring and evaluate their antimicrobial activity in a preliminary assessment.
Noor Ali Sabzi, May Mohammed Jawad
doaj   +1 more source

Preparation and diagnosis some heterocyclic compounds that derived from 1,3,4 – Thiadiazole compound derived from 1,3,4 – Thiadiazole compound [PDF]

open access: yesKirkuk Journal of Science, 2016
This search included synthesis of some heterocyclic compounds devired from 1,3,4- thiadiazol ring ,such as thaiazolidin -4-one substituents Azetidine -3- one and Azo dyes.
Ayad S. H. AL-Maaini Nazhan.KA AL-Luhiby
doaj   +1 more source

Synthesis and Reactivity of 3H-1,2-dithiole-3-thiones

open access: yesMolecules, 2021
3H-1,2-Dithiole-3-thiones are among the best studied classes of polysulfur-containing heterocycles due to the almost explosive recent interest in these compounds as sources of hydrogen sulfide as an endogenously produced gaseous signaling molecule.
Oleg A. Rakitin
doaj   +1 more source

Methods for the synthesis of polyhydroxylated piperidines by diastereoselective dihydroxylation: Exploitation in the two-directional synthesis of aza-C-linked disaccharide derivatives [PDF]

open access: yes, 2005
Background: Many polyhydroxylated piperidines are inhibitors of the oligosaccharide processing enzymes, glycosidases and glycosyltransferases. Aza-C-linked disaccharide mimetics are compounds in which saturated polyhydroxylated nitrogen and oxygen ...
Adam Nelson   +8 more
core   +3 more sources

Synthesis, characterization, and antimicrobial evaluation of new Schiff bases derived from vanillic acid conjugated to heterocyclic 4H-1,2,4-triazole-3-thiol [PDF]

open access: yesPharmacia, 2023
A multistep synthesis was established for the preparation of a new vanillic acid-1, 2, 4-1triazole-3-thiol conjugate (4). Finally, several aromatized aldehydes reacted with compound (4) to produce Schiff bases derivatives (5–11).
Noor Ali Hussein Sabzi   +1 more
doaj   +3 more sources

1,3-Oxazepane-4,7-Diones Compounds: 1Hand 13CNMR High-Resolution Spectroscopy (1D and 2D) [PDF]

open access: yes, 2011
“Oxazepine” refers to any seven-membered ring containing an oxygen and nitrogen atom. The 1,3-oxazepine is a branch of many types of the heterocyclic oxazepine [1–7].
Abdul Karim , Talaq Mohammad   +2 more
core   +1 more source

Microwave-Assisted Stereoselective Heterocyclization to Novel Ring d-fused Arylpyrazolines in the Estrone Series

open access: yesMolecules, 2019
Microwave-assisted syntheses of novel ring d-condensed 2-pyrazolines in the estrone series were efficiently carried out from steroidal α,β-enones and hydrazine derivatives. The ring-closure reaction of 16-benzylidene estrone 3-methyl ether with
Gergő Mótyán   +3 more
doaj   +1 more source

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