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The Application of Green Solvents in the Synthesis of S-Heterocyclic Compounds-A Review. [PDF]

open access: yesInt J Mol Sci
Kosmalski T   +6 more
europepmc   +1 more source

Thiotemplated Polyketide Chain Fusion and Reductive Cyclization Build the Reactive Butenolide Core of Malleicyprol

open access: yesAngewandte Chemie, EarlyView.
Malleicyprol, a virulence factor of notorious animal and human pathogens of the Burkholderia pseudomallei (BP) group, results from the fusion of two individual polyketide chains. The noncanonical condensation domain of the PKS–NRPS hybrid synthetase BurF forms an ester bond, and the terminal reductase domain mediates a reductive chain release followed ...
Jonas Fiedler   +5 more
wiley   +1 more source

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