Results 251 to 260 of about 1,890,045 (316)

Combined effects of species diversity and soil depth heterogeneity on plant functional groups and community productivity. [PDF]

PeerJ
Liu L, Cheng B.
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Advances in deciphering intratumoral versus peritumoral heterogeneity of infiltrating lymphocytes in pancreatic cancer: a spatial perspective. [PDF]

Transl Oncol
Zhao K, Yang Q, Yan Y, Zhu J, Zheng S.
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Not all plasma cells are made equal: well-hidden layers of heterogeneity. [PDF]

Front Immunol
Akessé AA, Bonaud A.
europepmc   +1 more source

Meta-analysis and systematic review: efficacy of probiotics in combination with standard therapies for rotavirus enteritis. [PDF]

Ann Med Surg (Lond)
Gao X, Zhang H, Yu Y, Chen J, Qu Y.
europepmc   +1 more source

Comparative Effectiveness of CagriSegma, Semaglutide, Cagrilintide and Tirzepatide in the Management of Overweight and Obesity: A Network Meta-Analysis of Randomized Clinical Trials. [PDF]

Endocrinol Diabetes Metab
Hamarsheh S, Jaber AR, Abu-Khazneh O, Andonie CR, Majadleh S, Zahran A, Ayesh H.   +6 more
europepmc   +1 more source

Prevalence and risk factors of gastro-oesophageal reflux disease in Saudi Arabia: a systematic review and meta-analysis. [PDF]

BMJ Open
Alhafid IA, Ismail MH, Alsulaiman RM, Alrezuk AM, Almalke HD, Shaikh AK, Abdul Salam A, Al-Quorain AA.   +7 more
europepmc   +1 more source

"Diagnostic Performance of Artificial Intelligence in Evaluating Tricuspid Regurgitation: A Systematic Review and Meta-Analysis". [PDF]

Clin Cardiol
Eini P, Serpoush H, Rezayee M, Kassulke M.   +3 more
europepmc   +1 more source