Results 111 to 120 of about 4,842 (250)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
On the area spectral efficiency improvement of heterogeneous network by exploiting the integration of macro-femto cellular networks [PDF]
, 2012 Heterogeneous networks are an attractive means of expanding mobile network capacity. A heterogeneous network is typically composed of multiple radio access technologies (RATs) where the base stations are transmitting with variable power.
Shakir, Muhammad +3 more
core +1 more source
IEEE Access, 2019 Due to recent developments in the cellular communication system, stochastic process implementation is necessary. The cellular communication system exhibits random patterns in various domains, thereby compelling the utilization of stochastic processes to ...
Faizan Qamar +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Energy Efficient Resource Allocation and Utilization in Future Heterogeneous Cellular Network [PDF]
, 2017 Future Mobile Heterogeneous Cellular Networks are emerging as promising technology in terms of high speed, low latency and ubiquitous connectivity. Providing energy efficient services in exponentially increasing user size and rigorous utilization of ...
Qahar, Abdul; Network Security Research Group, Faculty of Computer Science and Information Technology, Universiti Malaysia Sarawak. University of the Punjab Lahore, Pakistan. +3 more
core +1 more source
Heterogeneous Evolution of Breast Cancer Cells—An Endogenous Molecular-Cellular Network Study
BiologyBreast cancer heterogeneity presents a significant challenge in clinical therapy, such as over-treatment and drug resistance. These challenges are largely due to its obscure normal epithelial origins, evolutionary stability, and transitions on the cancer
Tianqi Li, Yong-Cong Chen, Ping Ao
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Network heterogeneity regulates steering in actin-based motility
Nature Communications, 2017 Protrusive cellular structures contain a heterogeneous density of actin, but whether this influences motility is not known. Using an in vitro system and modelling, here the authors show that local actin monomer depletion and network architecture can tune
Rajaa Boujemaa-Paterski +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source