Results 81 to 90 of about 6,378,755 (279)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Partial Interference Alignment for Heterogeneous Cellular Networks

open access: yesIEEE Access, 2018
The deployment of small cell base stations (BSs) can efficiently boost the network capacity. Cross-tier interference management is critical for the performance enhancement in such heterogeneous networks. Interference alignment provides an efficient way to achieve optimal degree-of-freedom in interference channels. However, it is not necessarily optimal
Longwei Wang, Qilian Liang
openaire   +3 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Multi-Way Relaying Techniques for Heterogeneous Cooperative Wireless Network: From Theory to Practice

open access: yesDianxin kexue, 2015
A heterogeneous network integration scheme based on cooperative relay technology was proposed, then the foundation of heterogeneous network was conceived through the relay node, with the aim to solve the transmission bottleneck between heterogeneous ...
Wei Chen, Ke Ke, Yanping Yang, Ou Li
doaj   +2 more sources

Investigation of Open‐Loop Transmit Power Control Parameters for Homogeneous and Heterogeneous Small‐Cell Uplinks

open access: yesETRI Journal, 2018
In Long Term Evolution (LTE) cellular networks, the transmit power control (TPC) mechanism consists of two parts: the open loop (OL) and closed loop. Most cellular networks consider OL/TPC because of its simple implementation and low operation cost.
Amir Haider   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Single-cell Transcriptional Analysis Reveals Novel Neuronal Phenotypes and Interaction Networks involved In the Central Circadian Clock

open access: yesFrontiers in Neuroscience, 2016
Single-cell heterogeneity confounds efforts to understand how a population of cells organizes into cellular networks that underlie tissue-level function. This complexity is prominent in the mammalian suprachiasmatic nucleus (SCN).
James Park   +10 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Interference management in heterogeneous cellular networks [PDF]

open access: yes, 2013
textHeterogeneous cellular networks (HCNs) – comprising traditional macro base stations (BSs) and heterogeneous infrastructure such as microcells, picocells, femtocells and distributed antennas – are fast becoming a cost-effective and essential way of ...
Xia, Ping
core  

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