Results 111 to 120 of about 231,021 (266)

Applications of novel optical imaging methods in the study of marine mollusks: A review

open access: yesJournal of Innovative Optical Health Sciences
Optical imaging has been pivotal in biological research (e.g., cellular/developmental biology) for over two centuries. Recent advances like super-resolution fluorescence and nonlinear optical microscopy enable nanoscale studies of live cells and animals,
Deliang Yu   +6 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

All-optical logic processing unit using Kerr nonlinearity of MXene

open access: yesNature Communications
Optical logic computing harnesses the speed of light and the high bandwidth of optical signals to achieve ultrafast, highly parallel and energy-efficient operations. In particular, all-optical logic gates can perform Boolean functions using only photons,
Yanqi Ge   +14 more
doaj   +1 more source

Enhancing Si3N4 Waveguide Nonlinearity with Heterogeneous Integration of Few-Layer WS2. [PDF]

open access: yesACS Photonics, 2021
Wang Y   +9 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

High-throughput exfoliation of multiferroic ternary oxide monolayers with high transition temperature and giant spin splitting

open access: yesnpj Computational Materials
Two-dimensional (2D) non-van der Waals (non-vdW) materials has garnered significant attention in recent years, driven by the remarkable properties inherent in their parent bulk.
Yongle Zhong   +4 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

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