Results 111 to 120 of about 260,326 (318)
Heterogeneous Integration of Solid-State Quantum Systems with a Foundry Photonics Platform. [PDF]
ACS Photonics, 2023 Weng HC +5 more
europepmc +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Heterogeneous Integration of Freestanding Bilayer Oxide Membrane for Multiferroicity. [PDF]
Adv Sci (Weinh), 2023 Kang KT +15 more
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Data integration through service-based mediation for web-enabled information systems [PDF]
, 2008 The Web and its underlying platform technologies have often been used to integrate existing software and information systems. Traditional techniques for data representation and transformations between documents are not sufficient to support a flexible ...
Zhu, Yaoling, Pahl, Claus
core
A universal metasurface transfer technique for heterogeneous integration. [PDF]
Nanophotonics, 2023 Zhang X +4 more
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Through-silicon via advanced packaging technology and its radio frequency applications
ChipThrough-silicon via (TSV) technology is widely recognized as one of the most promising interconnect solutions, owing to its ability to dramatically shorten interconnect paths, reduce package dimensions, decrease power consumption, and enhance device ...
Hongyu Yi +4 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source