Results 91 to 100 of about 1,151,520 (297)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Effects of city-size heterogeneity on epidemic spreading in a metapopulation: A reaction-diffusion approach

, 2012
We review and introduce a generalized reaction-diffusion approach to epidemic spreading in a metapopulation modeled as a complex network. The metapopulation consists of susceptible and infected individuals that are grouped in subpopulations symbolising ...
Lizana, Ludvig, Lund, Halvor, Simonsen, Ingve   +2 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Multi-agent reinforcement learning based dynamic optimization algorithm of CRE offset for heterogeneous networks

Tongxin xuebao, 2023
To cope with the high throughput demand caused by the proliferation of wireless network users, a multi-agent reinforcement learning based dynamic optimization algorithm of cell range expansion (CRE) offset was proposed for interference scenarios in macro-
Cheng ZHANG, Jiaye ZHU, Zening LIU, Yongming HUANG   +3 more
doaj  

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Efficient Resource Allocation with Improved Interference Mitigation in FFR-Aided OFDMA Heterogeneous Networksb

Journal of Electronic Science and Technology, 2019
Fractional frequency reuse (FFR) has recently emerged as an efficient inter-cell interference coordination technique for orthogonal frequency division multiple access (OFDMA) based multi-tier cellular networks due to its low complexity, minimal signaling
Sani Umar Abdullahi, Jian Liu, Seyed Alireza Mohadeskasaei   +2 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Data-Assisted Radio Resource Allocation in Shared Spectrum Multi-RAT Heterogeneous Network

IEEE Access
New Radio Unlicensed (NR-U) is the key representative access technology beyond 5G implementation to alleviate the spectrum crunch. NR-U shares a 5 GHz unlicensed band with WiFi, which has contention challenges for the coexisting systems due to physical ...
Salman Saadat, Sami Ahmed Haider, Waleed Ejaz, Amith Khandakar Md. Abdullah   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Heterogeneous Vehicular Networks [PDF]

, 2016
This brief examines recent developments in the Heterogeneous Vehicular NETworks (HETVNETs), integrating cellular networks with Dedicated Short-Range Communication (DSRC) for meeting the communications requirements of the Intelligent Transport System (ITS)services. Along with a review of recent literature, a unified framework of the HetVNET is presented.
Zheng, Kan, Zhang, Lin, Xiang, Wei, Wang, Wenbo   +3 more
openaire   +2 more sources