Results 221 to 230 of about 415,171 (314)

A Complex Heterogeneous Network Model of Disease Regulated by Noncoding RNAs: A Case Study of Unstable Angina Pectoris. [PDF]

Comput Intell Neurosci, 2022
Qi G, Xu Z, Dan H, Jia X, Jiang Q, Zhang A, Li Z, Liu X, Ma J, Zheng X, Li Z.   +10 more
europepmc   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

An Optimized Method for Batch Recovery Based on Erasure Coding in Heterogeneous Network. [PDF]

Sensors (Basel)
Song Y, Liu J, Tian Y, Wang B.
europepmc   +1 more source

SVMMDR: Prediction of miRNAs-drug resistance using support vector machines based on heterogeneous network. [PDF]

Front Oncol, 2022
Duan T, Kuang Z, Deng L.
europepmc   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Heterogeneous network approaches to protein pathway prediction. [PDF]

Comput Struct Biotechnol J
Nayar G, Altman RB.
europepmc   +1 more source

Heterogeneous network flow and Petri nets characterize multilayer complex networks. [PDF]

Sci Rep, 2022
Ademovic Tahirovic A, Angeli D, Strbac G.   +2 more
europepmc   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

DeepHeteroCDA: circRNA-drug sensitivity associations prediction via multi-scale heterogeneous network and graph attention mechanism. [PDF]

Brief Bioinform
Huang Z, Chen K, Xiao X, Fan Z, Zhang Y, Deng L.   +5 more
europepmc   +1 more source

Customised Intrusion Detection for an Industrial IoT Heterogeneous Network Based on Machine Learning Algorithms Called FTL-CID. [PDF]

Sensors (Basel), 2022
Abosata N, Al-Rubaye S, Inalhan G.
europepmc   +1 more source