Results 101 to 110 of about 3,636,839 (294)

Gibbs-Sampling-based Optimization for the Deployment of Small Cells in 3G Heterogeneous Networks [PDF]

, 2013
The growing popularity of mobile data services has placed great demands for wireless cellular networks to support higher-throughput. One way to meet the rapidly growing traffic demand is through heterogeneous network deployment, which uses a mixture of ...
Wang, Chih-Chun, Lin, Xiaojun, li, Xiaohang, Tang, Xiaojun   +3 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Peak Age of Information Optimization in Heterogeneous Aloha Networks

IEEE Open Journal of the Communications Society
Rapid advancements in Internet of Things (IoT) technology have promoted numerous novel applications that are sensitive to information timeliness. With different applications coexisting in one wireless network, each of which has heterogeneous traffic ...
Dewei Wu, Wen Zhan, Xinghua Sun, Jingjing Liu, Zhiheng Li   +4 more
doaj   +1 more source

Coalitional Games for Joint Co-Tier and Cross-Tier Cooperative Spectrum Sharing in Dense Heterogeneous Networks

IEEE Access, 2016
With the dense deployment of small cells in the next generation of mobile networks, the users from different tiers suffer from high downlink interferences. In this paper, we propose a game theoretic approach for joint co-tier and cross-tier collaboration
Mouna Hajir, Rami Langar, Francois Gagnon   +2 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Modeling Disruption Tolerance Mechanisms for a Heterogeneous 5G Network

IEEE Access, 2018
Delay/disruption tolerant networking (DTN) was proposed as an internetworking architecture to accommodate the frequent and lengthy link disruptions and/or long propagation delays that are typical of a challenging communication environment.
Ruhai Wang, Alaa Sabbagh, Scott C. Burleigh, Mahjabeen Javed, Shushi Gu, Jian Jiao, Qinyu Zhang   +6 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Context-aware handoff support for wireless access networks [PDF]

, 2010
Includes bibliographical references (leaves 98-102).The phenomenal emergence of several heterogeneous wireless networks and technologies has allowed users to have access to IP services anywhere, at anytime, from any network and with whatever terminal ...
Mokhesi, Mr Lekometsa, Mokhesi, Lekometsa   +1 more
core   +1 more source