Results 61 to 70 of about 215,587 (263)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Universal network representation for heterogeneous information networks [PDF]

open access: yes2017 International Joint Conference on Neural Networks (IJCNN), 2017
Network representation aims to represent the nodes in a network as continuous and compact vectors, and has attracted much attention in recent years due to its ability to capture complex structure relationships inside networks. However, existing network representation methods are commonly designed for homogeneous information networks where all the nodes
Ruiqi Hu   +5 more
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Shared carrier vertical network transformation algorithm in heterogeneous wireless networks

open access: yesTongxin xuebao, 2012
In order to enhance the spectrum efficiency in heterogeneous wireless networks,the idea of dynamic spectrum allocation (DSA) used in cognitive radio was introduced into the heterogeneous wireless networks,the idea of vertical handoff for multi-mode ...
Liang ZHAO   +3 more
doaj   +2 more sources

Cross-Tier Interference Alignment With Interfering Pair Selection in Uplink Heterogeneous Networks With Multiple Macrocells

open access: yesIEEE Access, 2018
In this paper, we have considered the uplink cross-tier interference in multi-macrocell heterogeneous network-system, where each macrocell consists of a number of small cells.
Yifei Xu   +5 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Variational Graph Convolutional Networks for Dynamic Graph Representation Learning

open access: yesIEEE Access
The ubiquitous and ever-evolving nature of cyber threats demands innovative approaches that can adapt to the dynamic relationships and structures within network data.
Aabid A. Mir   +4 more
doaj   +1 more source

Fuzzy-Based Game Theoretic Mobility Management for Energy Efficient Operation in HetNets

open access: yesIEEE Access, 2017
The dense deployment of heterogeneous networks (HetNets) has shown to be a promising direction to cope with the capacity demands in the future 5G wireless networks.
Karthik Vasudeva   +5 more
doaj   +1 more source

Breaking Down the Compatibility Problem in Smart Homes: A Dynamically Updatable Gateway Platform

open access: yesSensors, 2020
Smart home is one of the most promising applications of the Internet of Things. Although there have been studies about this technology in recent years, the adoption rate of smart homes is still low.
Linh-An Phan, Taehong Kim
doaj   +1 more source

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