Results 81 to 90 of about 348,123 (308)
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Public preferences for government spending in Canada
International Journal for Equity in Health, 2012 This study considers three questions: 1. What are the Canadian public’s prioritization preferences for new government spending on a range of public health-related goods outside the scope of the country’s national system of health insurance? 2.
Ramji Sabrina, Quiñonez Carlos
doaj +1 more source
Is there a Case for Public Provision of Private Goods if Preferences are Heterogeneous? An Example with Day Care [PDF]
A strong case for public provision of certain private goods has been established for an economy in which individuals have homogeneous preferences but differ in skill levels.
Sören Blomquist, Vidar Christiansen
core
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
A quantum game decision-making analysis of parking sharing behavior considering fairness preferences
Transportation Research Interdisciplinary PerspectivesParking constraints are particularly acute in the urban city center, but the many negative impacts of sharing private parking make owners living in central areas reluctant to share private parking.
Qingqi Wei, Guomei Xiao
doaj +1 more source
BMC Pregnancy and Childbirth, 2019 Background Canadian policies regarding the implementation and public coverage of non-invasive prenatal testing (NIPT) are heterogeneous and shifting, with NIPT being publicly covered for high-risk pregnancies in some provinces, but not others.
Stanislav Birko +7 more
doaj +1 more source
US Highway Privatization and Heterogeneous Preferences [PDF]
: We assess the welfare effects of highway privatization accounting for government’s behavior in setting the sale price, firms’ strategic behavior in setting tolls in various competitive environments, and motorists’ heterogeneous preferences for speedy ...
Clifford Winston, Jia Yan
core
Optimal Policy with Heterogeneous Preferences [PDF]
, 2014 Optimal policy rules—including those regarding income taxation, commodity taxation, public goods, and externalities—are typically derived in models with homogeneous preferences.
Kaplow, Louis
core +1 more source
Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz +3 more
wiley +1 more source