Results 1 to 10 of about 17,905 (214)
Capsaicin induces ferroptosis of NSCLC by regulating SLC7A11/GPX4 signaling in vitro
Scientific Reports, 2022 NSCLC is the first cause of cancer-related deaths in China and threatens life expectancy of the people. Novel drugs and treatment strategies are urgently required.
Xiao-Yan Liu +2 more
doaj +2 more sources
Bioactive black tea phytochemicals partially influenced doxorubicin sensitivity by modulation of NRF2-regulatory pathways in lung cancer [PDF]
Journal of Ayurveda and Integrative MedicineBackground: Lung cancer therapy resistance is often associated with the redox-regulatory nuclear factor erythroid 2-related factor-2 (NRF2)-Kelch-like ECH-associated protein1 (KEAP1) dysfunction.
Suchisnigdha Datta +2 more
doaj +2 more sources
KRAS G12C inhibition enhances efficacy to conventional chemotherapy in KRAS-mutant NSCLC [PDF]
Frontiers in OncologyDespite recent therapeutic advances, the adjuvant treatment of non-small cell lung cancer (NSCLC) remains a challenge. Reducing the risk of recurrence is still a concern, especially in the KRAS G12C population, for which platinum-based adjuvant ...
Alessandro Tubita +13 more
doaj +2 more sources
H23 Efficacy of lisinopril Vs hydrochlorothiazide in obese hypertensive patients [PDF]
American Journal of Hypertension, 1997 Matthew Weir, M Tuck
exaly +2 more sources
Less workplace parking with fully autonomous vehicles? [PDF]
Journal of Intelligent and Connected Vehicles, 2022 Purpose – Recent studies on commuter parking in an age of fully autonomous vehicles (FAVs) suggest, that the number of parking spaces close to the workplace demanded by commuters will decline because of the capability of FAVs to return home, to seek out (
Stefan Tscharaktschiew, Felix Reimann
doaj +1 more source
Frontiers in Oncology, 2021 PurposeThis study aimed to explore the circular RNA (circRNA/circ) profile engaged in non-small cell lung cancer (NSCLC) development and metastasis and to investigate potentially key carcinogenic circRNAs related to NSCLC.MethodsCircRNA profiles between ...
Qiushi Wang +8 more
doaj +1 more source
A study of PD-L1 expression in KRAS mutant non-small cell lung cancer cell lines exposed to relevant targeted treatments. [PDF]
PLoS ONE, 2017 We investigated PD-L1 changes in response to MEK and AKT inhibitors in KRAS mutant lung adenocarcinoma (adeno-NSCLC). PD-L1 expression was quantified using immunofluorescence and co-culture with a jurkat cell-line transfected with NFAT-luciferase was ...
Anna Minchom +10 more
doaj +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021 As one of the most lethal malignancies, lung cancer is considered to account for approximately one-fifth of all malignant tumours-related deaths worldwide.
Mohammad M. Al-Sanea +9 more
doaj +1 more source
MiR-326 mediates malignant biological behaviors of lung adenocarcinoma by targeting ZEB1
Science Progress, 2021 MiR-326 functions as an antioncogene in the several types of cancer. However, the underling mechanisms through which miRNA-326 regulates the anti-carcinogenesis of lung adenocarcinoma have remained elusive.
Mingxin Liu +11 more
doaj +1 more source
Molecular Therapy: Nucleic Acids, 2019 Paclitaxel (PTX) is a widely used chemotherapy drug; however, frequent use causes multidrug resistance (MDR), which limits the utility of PTX against advanced non-small-cell lung cancer (NSCLC).
Wangta Liu +9 more
doaj +1 more source