Results 21 to 30 of about 17,190 (226)
PurposeThis study aimed to explore the circular RNA (circRNA/circ) profile engaged in non-small cell lung cancer (NSCLC) development and metastasis and to investigate potentially key carcinogenic circRNAs related to NSCLC.MethodsCircRNA profiles between ...
Qiushi Wang +8 more
doaj +1 more source
A study of PD-L1 expression in KRAS mutant non-small cell lung cancer cell lines exposed to relevant targeted treatments. [PDF]
We investigated PD-L1 changes in response to MEK and AKT inhibitors in KRAS mutant lung adenocarcinoma (adeno-NSCLC). PD-L1 expression was quantified using immunofluorescence and co-culture with a jurkat cell-line transfected with NFAT-luciferase was ...
Anna Minchom +10 more
doaj +1 more source
Background: Carbonylated proteins (CPs) serve as specific indicators of increased reactive oxygen and nitrogen species (RONS) production in cancer cells, attributed to the dysregulated mitochondrial energy metabolism known as the Warburg effect.
Joachim Greilberger +4 more
doaj +1 more source
As one of the most lethal malignancies, lung cancer is considered to account for approximately one-fifth of all malignant tumours-related deaths worldwide.
Mohammad M. Al-Sanea +9 more
doaj +1 more source
MiR-326 mediates malignant biological behaviors of lung adenocarcinoma by targeting ZEB1
MiR-326 functions as an antioncogene in the several types of cancer. However, the underling mechanisms through which miRNA-326 regulates the anti-carcinogenesis of lung adenocarcinoma have remained elusive.
Mingxin Liu +11 more
doaj +1 more source
Paclitaxel (PTX) is a widely used chemotherapy drug; however, frequent use causes multidrug resistance (MDR), which limits the utility of PTX against advanced non-small-cell lung cancer (NSCLC).
Wangta Liu +9 more
doaj +1 more source
Despite numerous favourable consequences, excessive smartphone usage has been linked to behaviours that might be detrimental or unsettling, at least for some individuals.
Saqib Nawaz
doaj +1 more source
The study examined the influence of skill mapping and talent pool management on organisational development in Nigeria. The study adopted a survey research and the study population comprised three thousand (3000) active members of Chartered Institute of ...
Abioro Matthew Adekunle +3 more
doaj +1 more source
Effect of Informal Sector Tax Revenue on Capital Development in Lagos Metropolis
The study investigates the effect of informal sector tax proceeds on capital development in Lagos Metropolis. The study adopted Ex-post facto design to obtain secondary data, covering 20 years (2000–2019) from the Lagos State Internal Revenue Service and
Olabisi Jayeola +3 more
doaj +1 more source
Glycyrrhizin Suppresses Lung Adenocarcinoma Cell Growth Through Inhibition of Thromboxane Synthase
Background/Aims: The effects of glycyrrhizin treatment in lung cancer remain undetermined, despite extensive studies of the anti-tumor activities of glycyrrhizin. Methods: Lung adenocarcinoma A549 and NCI-H23 cell lines were used in this study.
Run-Yue Huang +5 more
doaj +1 more source

