Characterization and modification of phenolic acid decarboxylase from marine bacteria for the synthesis of 4-vinyl phenol derivatives [PDF]
Background The 4-vinyl derivatives of various hydroxycinnamic acids are highly valued for their substantial application in the food and other industries.
Liying Zhang +9 more
doaj +2 more sources
Botulinum Neurotoxin F Subtypes Cleaving the VAMP-2 Q58–K59 Peptide Bond Exhibit Unique Catalytic Properties and Substrate Specificities [PDF]
In the recent past, about 40 botulinum neurotoxin (BoNT) subtypes belonging to serotypes A, B, E, and F pathogenic to humans were identified among hundreds of independent isolates. BoNTs are the etiological factors of botulism and represent potential bioweapons; however, they are also recognized pharmaceuticals for the efficient counteraction of ...
Thomas Binz +2 more
exaly +8 more sources
Establishment of a humanized SCA2 mouse model carrying a CAA disruption preventing CAG repeat expansion in pathogenic genes. [PDF]
In this study, we established a mouse model in which CAG repeats do not undergo microsatellite instability (MSI) across generations. A humanized ATXN2 cDNA with four CAA interruptions within 73 CAG expansions was inserted into the Rosa26 locus of C57BL/6J mice. At the same time, a 23 CAG control mouse model was also generated.
Zhang Y +9 more
europepmc +2 more sources
Barriers to Changing Sedation Practice for Patients Undergoing Mechanical Ventilation on the Intensive Care Unit: A Qualitative Interview Study of Clinical Staff. [PDF]
ABSTRACT Background Medical sedation is a requirement for mechanical ventilation for most patients admitted to the intensive care unit (ICU). Sedation can help minimise patient discomfort, pain and distress, but can lead to hypotension, bradycardia, prolonged ventilation and delirium.
Richards ND, Bekker HL, Howell SJ.
europepmc +2 more sources
Multifractal analysis of atmospheric carbon emissions and OECD industrial production index [PDF]
Purpose – The purpose of this study aims to analyze the dynamic behavior of the relationship between atmospheric carbon emissions and the Organisation for Economic Co-operation and Development (OECD) industrial production index (IPI) in the short and ...
Sezer Kahyaoglu Bozkus +2 more
doaj +1 more source
The Impact of the Polish Renewable Energy Sector on Employment
Subject and purpose of work: This study analyses employment in the renewable energy sector. The aim of this research was to explore the impact of obtaining energy from renewable sources on the labor market in Poland.
Gradziuk Piotr Lucjan
doaj +1 more source
Medio ambiente y desarrollo en un contexto centro-periferia
El crecimiento económico, que ha posibilitado un incremento en los niveles de bienestar, ha tenido como consecuencia inmediata la degradación ambiental por consumo neto de naturaleza y por contaminación.
José Luis Samaniego +2 more
doaj +1 more source
Emisiones de gases de efecto invernadero y sectores clave en Colombia
El incremento de la temperatura en los últimos 50 años ha tenido serios efectos sobre la economía, por lo cual es necesario tomar medidas de mitigación para atenuar sus efectos.
Gustavo Hernández
doaj +1 more source
Effectiveness of environmental policies on carbon emissions: A panel threshold analysis
The aim of this study is to test the possible non-linear effect of environmental policy stringency on carbon emissions and thus make policy recommendations for emission reduction.
Akbulut Hale
doaj +1 more source
Carbon Leakage Along with the Green Paradox Against Carbon Abatement? A Review Based on Carbon Tax
Research background: Insufficient global cooperation in carbon pricing against global warming has the risk of global carbon emissions rise because of carbon leakage.
Akkaya Sahin, Bakkal Ufuk
doaj +1 more source

