Results 31 to 40 of about 618 (148)

The Role of DEI and Meaningful Work in the Relationship Between CSR and Organizational Commitment

open access: yesBusiness Strategy &Development, Volume 9, Issue 1, March 2026.
ABSTRACT The aim of this paper is to determine whether corporate social responsibility (CSR) practices have a positive effect on employees' organizational commitment, considering diversity, equity, and inclusion (DEI) as a mediating variable and meaningful work as a moderating variable in this relationship.
José Manuel González‐Soberado   +1 more
wiley   +1 more source

Glyoxalase‐1 Inhibition Leads to Ferroptosis Induction in Lung Cancer Cells: A Dual Mechanism of Action of Hydroxamic Acids Derived from Cysteine

open access: yesChemMedChem, Volume 21, Issue 1, January 2026.
A set of three cysteine‐derived hydroxamic acids were synthesized and evaluated for human gloxalase‐1 inhibition and ferroptosis induction activities. Among them, compound 2 exhibited a potent inhibitory effect against human glyoxalase‐1 and induced ferroptosis in non‐small cell lung cancer cell lines, increasing reactive oxygen species production and ...
Josué Martínez‐Miranda   +7 more
wiley   +1 more source

Assessing the Perceived Fairness of a Property Tax by a Taxpayer Survey: The Case of Residential Arnona Tax in Israel

open access: yesReal Estate Management and Valuation
Understanding taxpayer perceptions of a property tax system is essential for developing equitable and transparent fiscal policies that foster public trust.
Mintz Mordekhay, Portnov Boris A.
doaj   +1 more source

El imperialismo climático en el siglo XXI

open access: yesEl Trimestre Económico, 2023
El artículo plantea que hay una nueva forma de imperialismo en el siglo XXI, gracias al cambio climático, sus causas antropogénicas en particular, originadas por la explotación desmedida de parte de los países desarrollados- y los impactos que está ...
Jayati Ghosh   +2 more
doaj   +1 more source

Barriers to Changing Sedation Practice for Patients Undergoing Mechanical Ventilation on the Intensive Care Unit: A Qualitative Interview Study of Clinical Staff

open access: yesNursing in Critical Care, Volume 31, Issue 1, January 2026.
ABSTRACT Background Medical sedation is a requirement for mechanical ventilation for most patients admitted to the intensive care unit (ICU). Sedation can help minimise patient discomfort, pain and distress, but can lead to hypotension, bradycardia, prolonged ventilation and delirium.
Nicholas D. Richards   +2 more
wiley   +1 more source

Characterization and modification of phenolic acid decarboxylase from marine bacteria for the synthesis of 4-vinyl phenol derivatives

open access: yesBMC Microbiology
Background The 4-vinyl derivatives of various hydroxycinnamic acids are highly valued for their substantial application in the food and other industries.
Liying Zhang   +9 more
doaj   +1 more source

Amyloid Forming Human Lysozyme Intermediates are Stabilized by Non‐Native Amide‐π Interactions

open access: yesAdvanced Science, Volume 12, Issue 34, September 11, 2025.
Mutational variants of human lysozyme cause fatal systemic amyloidosis by depositing kilograms of protein in the viscera of patients. Central to this process is a partially unfolded protein intermediate state that initiates aggregation into amyloid fibrils.
Minkoo Ahn   +6 more
wiley   +1 more source

Establishment of a humanized SCA2 mouse model carrying a CAA disruption preventing CAG repeat expansion in pathogenic genes

open access: yesAnimal Models and Experimental Medicine, Volume 8, Issue 9, Page 1677-1687, September 2025.
In this study, we established a mouse model in which CAG repeats do not undergo microsatellite instability (MSI) across generations. A humanized ATXN2 cDNA with four CAA interruptions within 73 CAG expansions was inserted into the Rosa26 locus of C57BL/6J mice. At the same time, a 23 CAG control mouse model was also generated.
Yao Zhang   +9 more
wiley   +1 more source

Concerns regarding the sustainable development of energy – opportunities and challenges for RES adoption in Poland

open access: yesInternational Journal of Management and Economics
Energy transition is a time- and capital-intensive process, particularly in the shift from fossil fuels to renewable energy sources (RES). Poland exemplifies this transition, navigating fluctuations in energy prices. The invasion of Ukraine by Russia has
Przedworska Kornelia   +4 more
doaj   +1 more source

Intramolecular epistasis correlates with divergence of specificity in promiscuous and bifunctional NSAR/OSBS enzymes

open access: yesProtein Science, Volume 34, Issue 5, May 2025.
Abstract Understanding the functions and evolution of specificity‐determining residues is essential for improving strategies to predict and design enzyme functions. Whether the function of an amino acid residue is retained during evolution depends on intramolecular epistasis, which occurs when the same residue contributes to different phenotypes in ...
Dat P. Truong   +14 more
wiley   +1 more source

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