Results 41 to 50 of about 1,606,057 (299)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

A preliminary analysis of base saturation flow rate during first loss time and saturated time at pretimed signalized intersections [PDF]

E3S Web of Conferences
Saturation flow rate is a key parameter essential for assessing signalized intersection capacity. The reference often used for signalized intersection planning in Indonesia is Indonesian Highway Capacity Guidelines (PKJI, 2023).
Syahrul Fazila Teuku, Sugiarto Sugiarto, Saleh Sofyan M., Rusdi Muhammad   +3 more
doaj   +1 more source

Heterogeneous Mixed Traffic Control and Coordination

2025 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS)
IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS ...
Iftekharul Islam, Weizi Li, Xuan Wang, Shuai Li, Kevin Heaslip   +4 more
openaire   +4 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Modelling vehicular behaviour using trajectory data under non-lane based heterogeneous traffic conditions [PDF]

Archives of Transport, 2019
The present study aims to understand the interaction between different vehicle classes using various vehicle attributes and thereby obtain useful parameters for modelling traffic flow under non-lane based heterogeneous traffic conditions. To achieve this,
Hari Krishna Gaddam, K. Ramachandra Rao
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Optimal Lane Allocation Strategy in Toll Stations for Mixed Human-Driven and Autonomous Vehicles

Applied Sciences
Highway toll stations are equipped with electronic toll collection (ETC) lanes and manual toll collection (MTC) lanes. It is anticipated that connected autonomous vehicles (CAVs), MTC human-driven vehicles (MTC-HVs), and ETC human-driven vehicles (ETC ...
Zuoyu Chai, Tanghong Ran, Min Xu
doaj   +1 more source

Adaptive Path Selection Algorithm with Flow Classification for Software-Defined Networks

Mathematics, 2023
Software-Defined Networking (SDN) is a trending architecture that separates controller and forwarding planes. This improves network agility and efficiency.
Muhammed Nura Yusuf, Kamalrulnizam bin Abu Bakar, Babangida Isyaku, Ahmed Hamza Osman, Maged Nasser, Fatin A. Elhaj   +5 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Bus travel time prediction using support vector machines for high variance conditions

Transport, 2021
Real-time bus travel time prediction has been an interesting problem since past decade, especially in India. Popular methods for travel time prediction include time series analysis, regression methods, Kalman filter method and Artificial Neural Network ...
Anil Kumar Bachu, Kranthi Kumar Reddy, Lelitha Vanajakshi   +2 more
doaj   +1 more source