Results 211 to 220 of about 440,074 (404)

Model-guided chemical environment and metabolic network design to couple pathways with cell fitness. [PDF]

Metab Eng Commun
Kakko von Koch N, Tenkanen T, Castillo S, Vidgren V, Koponen T, Krogerus K, Penttilä M, Jouhten P.   +7 more
europepmc   +1 more source

THE IMMUNE RESPONSE OF RABBITS TOLERANT TO BOVINE SERUM ALBUMIN TO THE INJECTION OF OTHER HETEROLOGOUS SERUM ALBUMINS [PDF]

, 1961
William O. Weigle
openalex   +1 more source

Neurodevelopmental features in KCNQ2 developmental and epileptic encephalopathy may have limited associations with KV7.2 dysfunction

Epilepsia Open, EarlyView.
Abstract Objective Variants in KCNQ2 encoding the voltage‐gated potassium channel KV7.2 are associated with developmental and epileptic encephalopathy (DEE) of varying severity. This study examined the relationship of KCNQ2 variant dysfunction with the neurodevelopmental phenotype of individuals with KCNQ2‐DEE. Methods A parent‐reported survey gathered
Jessa S. Bidwell, Carlos G. Vanoye, Reshma R. Desai, Anne T. Berg, Alfred L. George Jr   +4 more
wiley   +1 more source

Optimized multi-epitope neoantigen human cytomegalovirus vaccine based on adenovirus vectors elicits potent antiviral immunity. [PDF]

Front Immunol
Jiang S, Zhang X, Zhao H, Liu F, Li Z, Yang X, Liu W, Lv J, Zhang Y, Zhang Y, Yu Y, Wang B, Wang Y.   +12 more
europepmc   +1 more source

Personalized Cancer Immunotherapy Boosted by cGAS‐STING‐Targeted Nanovaccines in Combination With Nutrient Modulation

Exploration, EarlyView.
The engineered bacteria (2'3'‐cGAMP@E.coli) is designed to synthesize intracellular 2'3'‐cGAMP, enabling the assembly of personalized nanovaccines (nECTs) through a bioconjugation with autologous tumor antigens, circumventing elaborate chemical production processes. The therapeutic impact of nECTs is significantly amplified when combined with a fasting‐
Wenping Huang, Guoliang Cao, Mixiao Tan, Fuhao Jia, Jie Zhang, Wen Su, Yue Yin, Hai Wang   +7 more
wiley   +1 more source

Heterologous biosynthetic crosstalk with the native mansouramycin cluster in <i>Streptomyces albus</i> Del14 reveals unexpected metabolites. [PDF]

RSC Chem Biol
Stierhof M, Horbal L, Oberhäuser P, Palusczak A, Cox P, Lopatniuk M, Ruf C, Zapp J, Luzhetskyy A.   +8 more
europepmc   +1 more source

P04 A NOVEL MOUSE MODEL OF MEMBRANOUS NEPHROPATHY INDUCED WITH HETEROLOGOUS RABBIT ANTI-THSD7A ANTIBODIES

, 2016
Nicola M. Tomas, Catherine Meyer‐Schwesinger, Hanning von Spiegel, Gunther Zahner, Elion Hoxha, Udo Helmchen, F Koch-Nolte, Rolf A.K. Stahl   +7 more
openalex   +1 more source

A Comprehensive Review of Probiotics in Alleviating Hyperuricemia: Mechanisms, Strain Engineering, and Food Applications

Food Bioengineering, EarlyView.
Screening and modification of probiotics that can efficiently reduce uric acid provide a new strategy for food‐grade hyperuricemia intervention. ABSTRACT Hyperuricemia has become one of the most prevalent global epidemics, significantly impacting both the economy and the health of individuals.
Le Wang, Qi Wu, Mengjia Zhang, Zifu Ni, Pengshuai Zhang, Siyuan Bai, Yibin Wang, Zhongke Sun   +7 more
wiley   +1 more source

The Paclitaxel Biosynthesis Pathway Unlocked. [PDF]

Research (Wash D C)
Martinelli L, Papon N, Courdavault V.
europepmc   +1 more source

Development of Komagataella phaffii Cell‐Free Protein Synthesis Using Cell From Basic Salt Medium

Food Bioengineering, EarlyView.
This process illustrates a three‐step procedure for K. phaffii CFPS setup. First, K. phaffii cells are cultivated in basic salt medium and harvested by centrifugation. Then, cell extract is prepared from cell pellets through ultrasonic disruption, dialysis, centrifugation, and lyophilisation. Finally, K.
Yu Zhang, Yue Wang, Wenjie Cong, Hualan Zhou, Jianguo Zhang   +4 more
wiley   +1 more source