Results 281 to 290 of about 361,202 (360)

Installing a Ketocarotenoid Branch in <i>Phaeodactylum tricornutum</i> via Functional Activation of <i>Chlamydomonas reinhardtii</i> β-Carotene Ketolase. [PDF]

Mar Drugs
Chao H, Kamal R, Wu Y, Huang D, Wang C.
europepmc   +1 more source

Structural analysis of the NifL‐NifA complex reveals the molecular basis of anti‐activation of nitrogen fixation gene expression in Azotobacter vinelandii

The FEBS Journal, EarlyView.
Using cryo‐EM combined with biochemical and genetic approaches, we mapped the interaction surface between NifL and NifA to gain insights into the regulation of nitrogen fixation genes in A. vinelandii. Our findings suggest that NifL, a homolog of histidine kinases lacking phosphorylation activity, evolved to act as a steric block of NifA activity ...
Marcelo Bueno Batista, Jake Richardson, Michael W. Webster, Dmitry Ghilarov, John W. Peters, David M. Lawson, Ray Dixon   +6 more
wiley   +1 more source

Heterologous DNA-Adenovirus Prime-Boost Strategy Expressing Bluetongue Virus VP2 and VP7 Proteins Protects Against Virulent Challenge. [PDF]

Vaccines (Basel)
Nogales-Altozano P, Gómez-Marcos L, Carlón AB, Louloudes-Lázaro A, Rivera-Rodríguez A, Larraga J, Alcolea PJ, Alonso A, Larraga V, Martín V, Rojas JM, Sevilla N.   +11 more
europepmc   +1 more source

Cas9 beyond CRISPR – SUMOylation, effector‐like potential and pathogenic adaptation

The FEBS Journal, EarlyView.
This Viewpoint explores the possibility that Cas9, beyond its canonical role in CRISPR immunity, may act as a host‐modulating effector during infection by Cas9‐encoding bacteria. Such a nucleomodulin‐like function could be influenced by eukaryotic post‐translational modifications, particularly SUMOylation, with potential implications for host–pathogen ...
Umut Sahin
wiley   +1 more source

Metabolic engineering of Phaeodactylum tricornutum for heterologous production of the plant triterpenoid friedelin. [PDF]

Microb Cell Fact
Nguyen K, Choi MS, Seo S, Song J, Jin E.
europepmc   +1 more source

Heterologous plastoquinone production using a newly identified O2‐dependent cyanobacterial hydroxylase

The FEBS Journal, EarlyView.
In this study, we confirm that PlqH is the hydroxylase operating in plastoquinone biosynthesis in photosynthetic cyanobacteria (Cyanobacteriia). Our phylogenetic analyses demonstrate that cyanobacterial PlqH homologues originated from hydroxylases involved in ubiquinone biosynthesis in bacteria. Plastoquinone production in Escherichia coli was achieved
Morgane Roger‐Margueritat, Margot Beltran, Juliette Schnoebelen, Laura Flandrin, Wafa Rezali, Eline Michel, Sophie S. Abby, Fabien Pierrel   +7 more
wiley   +1 more source

Comment on “Effectiveness of homologous or heterologous immunization regimens against SARS-CoV-2 after two doses of inactivated COVID-19 vaccine: A systematic review and meta-analysis”

Human Vaccines & Immunotherapeutics
Amin Sharifan
doaj   +1 more source

Binding of Bacillus subtilis dynamin‐like protein DynA to the bacterial membrane is essential for effective phage defense

The FEBS Journal, EarlyView.
The bacterial dynamin‐like protein DynA from Bacillus subtilis plays a key role in phage defense. It binds the plasma membrane through a unique paddle domain in its D1 subunit. This membrane association is essential for its protective function, likely preventing explosive membrane rupture following phage infection.
Samia Shafqat, Urska Repnik, Marc Bramkamp   +2 more
wiley   +1 more source

Novel HIV-1 fusion peptide immunogens using glycan-engineered alphavirus-like particles. [PDF]

NPJ Vaccines
Oh SH, Gudipati DR, Shi W, Zhao P, Wu W, Boyington JC, Nariya HK, McGhee EG, Azzam T, Raghunathan V, Yang C, Yang C, Lee C, Kim JD, Zhou T, Mascola JR, Wells L, Kong R.   +17 more
europepmc   +1 more source