Results 151 to 160 of about 145,939 (263)

Characterization of Caenorhabditis elegans sphingomyelin synthases through heterologous expression. [PDF]

J Biol Chem
Guzman G, Jahn H, Farley SE, Kyle JE, Bramer LM, Hoetzl S, van den Dikkenberg J, Hermansson M, Holthuis JCM, Tafesse FG.   +9 more
europepmc   +1 more source

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

Andrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos, Marie‐Pier Scott‐Boyer, Arnaud Droit, Robert S. Viger, Jacques J. Tremblay   +4 more
wiley   +1 more source

Heterologous Expression, Enzymatic Characterization, and Ameliorative Effects of a Deoxynivalenol (DON)-Degrading Enzyme in a DON-Induced Mouse Model. [PDF]

Toxins (Basel)
Zhou H, Xu B, Peng Y, Mao J, Zhang X, Guo Y, Zhang Y.   +6 more
europepmc   +1 more source

Microtubule Inner Protein CFAP77 Contributes to Sperm Motility and Male Fertility in Mice

Andrology, EarlyView.
ABSTRACT Background Sperm motility is essential for male fertility, and its regulation is dependent on the structural integrity of the axoneme. The axoneme consists of a conserved “9+2” microtubule arrangement and is supported by microtubule inner proteins. However, the functional significance of many microtubule inner proteins remains unclear.
Haoting Wang, Anh Hoang Pham, Mengjiao Luo, Masahito Ikawa, Haruhiko Miyata   +4 more
wiley   +1 more source

A novel signal peptide toolbox for optimized heterologous expression of yeast pheromones in Bacillus subtilis. [PDF]

J Genet Eng Biotechnol
Vološen T, Deda HM, Walther A, Popp PF, Mascher T, Wolf D.   +5 more
europepmc   +1 more source

The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations

Acta Paediatrica, EarlyView.
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley   +1 more source

Heterologous expression and foldase-assisted refolding of LipGoM, a <i>Pseudomonas</i> lipase from family I. [PDF]

Biochem Biophys Rep
Garcia-Villegas EL, Hidalgo-Manzano IA, Pardo-López L, Rudiño-Piñera E.   +3 more
europepmc   +1 more source

Tau‐targeting active immunotherapy slows progression and reduces pathology in mouse models of tauopathy

Brain Pathology, EarlyView.
The efficacy of the novel anti‐tau active immunotherapy, p5555kb, was tested using two mouse models of tau pathology. p5555kb inoculation increased the survival rate and reduced tau pathology in tau‐overexpressing P301L mice and decreased tau seeding in the brains of C57BL/6 mice injected with human‐purified Alzheimer's disease tau.
Christopher M. Brown, Jeanne K. Brooks, Louise Kelly, Madeline M. Vroom, Matthew Longo, Jean‐Cosme Dodart, Roxana Carare, Justin D. Boyd   +7 more
wiley   +1 more source

Cloning, heterologous expression, and expression analysis of SinSyn7 gene from Sinomenium acutum. [PDF]

PLoS One
Chen J, Chen X, Zhang L, Huang S, Chen X, Huang X, Yang H.   +6 more
europepmc   +1 more source