Results 181 to 190 of about 3,478,631 (289)

Induction and Enhancement of Bacteriocin Production (Review)

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Conventionally, bacteriocins are produced by microorganisms on complex substrates, released as semi‐purified preparations or crude fermentates. These bacteriocin‐containing products often exhibit unsatisfactory purity, low active‐substance content, and high production costs, limiting their commercialization and use. This review aims to analyze
Oksana Knysh, Artur Martynov
wiley   +1 more source

Improving autotrophic D-lactate production by heterologous expression of a pyruvate formate lyase in an LDHD-expressing Acetobacterium woodii strain. [PDF]

Appl Microbiol Biotechnol
Baur KS, Stock A, Weuster-Botz D, Bengelsdorf FR.   +3 more
europepmc   +1 more source

Autonomous Control of Gene Expression Using Endogenous Transcription Signals

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Autonomous cell‐based control of heterologous gene expression can simplify batch‐culture bioprocessing by eliminating external monitoring and extrinsic control of culture conditions. Existing approaches use auto‐induction media, synthetic cell‐cell communication systems, or application‐specific biosensors.
Pakpoom Subsoontorn, Drew Endy, Olivier Borkowski   +2 more
wiley   +1 more source

Heterologous expression, structural analysis, and functional characterization of Ostrinia nubilalis pheromone-binding protein 2 (OnubPBP2). [PDF]

Sci Rep
Nukala V, Al-Danoon O, Mohanty S.
europepmc   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

Establishing synthetic ribbon-type active zones in a heterologous expression system. [PDF]

Elife
Kapoor R, Do TT, Schwenzer N, Petrovic A, Dresbach T, Lehnart SE, Fernández-Busnadiego R, Moser T.   +7 more
europepmc   +1 more source

Exosome‐mimetic vesicle‐encapsulated multi‐responsive antibacterial hydrogel core‐shell microneedle patch promotes scarless healing of infected wounds

BMEMat, EarlyView.
The core‐shell microneedle patch VP@FNV‐CuO2‐MN was fabricated by encapsulating n‐CuO2 in a moderately crosslinked PVA/CMCS/Borax4 hydrogel shell and VP‐loaded fibroblast membrane nanovesicles (VP@FNV) in a highly crosslinked PVA/CMCS/Borax6 hydrogel core. Upon application to an infected wound, the acidic microenvironment triggers Fenton‐like reactions
Ziwei Jiang, Huihui Zhang, Lianglong Chen, Zhangfeifan Yang, Sai Cao, Yufang He, Xiaoyang Liu, Siew Yee Wong, Xu Li, Hai Zhou, Ziyan Li, Zijun Zheng, Lei Yang   +12 more
wiley   +1 more source

Heterologous Expression of a <i>Neurospora crassa</i> Catalase Reprograms the Cellulase System and Enhances β-Glucosidase Production in <i>Trichoderma reesei</i>. [PDF]

J Fungi (Basel)
Sun H, Tang C, Chen Y, Zhang Y, You W, Su S, Zhao H, Huang J, Jiang X, Qin L.   +9 more
europepmc   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Functional identification of key enzymes in calycosin biosynthesis in <i>Astragalus membranaceus</i> and establishment of heterologous expression system. [PDF]

Pharm Sci Adv
Cui MX, Hao Y, Li JN, Xu DD, Hao PX, Fu J, Lu Y, Li YT, Zhi LL, Zhang JZ, Lou HX, Cheng AX.   +11 more
europepmc   +1 more source