Results 41 to 50 of about 1,367 (116)

c-Src/Cav1-dependent activation of the EGFR by Dsg2. [PDF]

, 2016
The desmosomal cadherin, desmoglein 2 (Dsg2), is deregulated in a variety of human cancers including those of the skin. When ectopically expressed in the epidermis of transgenic mice, Dsg2 activates multiple mitogenic signaling pathways and increases ...
Brennan-Crispi, Donna M., Cooper, Felicia, Deguchi, Takahiro, Mahoney, Mỹ G., McGuinn, Kathleen P., Overmiller, Andrew M., Peltonen, Sirkku, Roberts, Brett J., Wahl, James K.   +8 more
core   +2 more sources

Comparison of Enzyme‐Linked Immunosorbent Assay and Lateral Flow Assay to Measure Thyroid‐Stimulating Hormone and Free T4 in Human Serum

Journal of Clinical Laboratory Analysis, Volume 39, Issue 10, May 2025.
TSH and fT4 measured by EIA and EFL were evaluated by two regression models: Deming and Passing Bablok. The Deming regression for TSH shows that the mean levels obtained by both methods do not present significant differences; however, the Passin‐Bablok regression identifies significant bias between both methods in the range of concentrations studied ...
Rolando Advíncula‐Espino, Jair Li, Jaime Rosales‐Rimache   +2 more
wiley   +1 more source

A catenin-dependent balance between N-cadherin and E-cadherin controls neuroectodermal cell fate choices [PDF]

, 2018
Characterizing endogenous protein expression, interaction and function, this study identifies in vivo interactions and competitive balance between N-cadherin and E-cadherin in developing avian (Gallus gallus) neural and neural crest cells.
Bronner, Marianne E., Rogers, Crystal D., Sorrells, Lisa K.   +2 more
core   +1 more source

Regulation of dendrimer/dextran material performance by altered tissue microenvironment in inflammation and neoplasia [PDF]

, 2015
available in PMC 2015 October 30A “one material fits all” mindset ignores profound differences in target tissues that affect their responses and reactivity.
Artzi, Natalie, Beckerman, Margarita, Carcole Solanes, Maria, Edelman, Elazer R., Hayward, Alison, Oliva Jorge, Nuria, Parry, Nicola, Seliktar, Sivan, Stanley, Butch   +8 more
core   +1 more source

EGCG Alleviates H2O2‐Induced Inflammatory Injury and Apoptosis in Bovine Mammary Epithelial Cells Through Nrf2 Pathway Activation and p38MAPK Pathway Inhibition

Food Science &Nutrition, Volume 13, Issue 3, March 2025.
The present study sought to investigate the protective effects of epigallocatechin‐3‐gallate (EGCG) on hydrogen peroxide‐induced oxidative stress, inflammation, and apoptosis, and related mechanisms. The test showed that EGCG could improve the antioxidant function of bovine mammary epithelial cells by activating the Nrf2 and inhibiting the p38 mitogen ...
Xuehu Ma, Chunli Hu, Yanhao An, Xue Feng, Peipei Cao, Yun Ma, Yanfen Ma   +6 more
wiley   +1 more source

Altered nerve terminal arborization and synaptic transmission in Drosophila mutants of cell adhesion molecule fasciclin I [PDF]

, 1995
This work investigates the role of cell adhesion molecules in development of synaptic connections and functions through a genetic approach. Fasciclin I (Fas I) is an insect glycoprotein capable of mediating homophilic cell adhesion.
Shanley, J., Zhong, Y.
core   +1 more source

THeGCN: Temporal Heterophilic Graph Convolutional Network

CoRR
Graph Neural Networks (GNNs) have exhibited remarkable efficacy in diverse graph learning tasks, particularly on static homophilic graphs. Recent attention has pivoted towards more intricate structures, encompassing (1) static heterophilic graphs encountering the edge heterophily issue in the spatial domain and (2) event-based continuous graphs in the ...
Yan, Yuchen, Chen, Yuzhong, Chen, Huiyuan, Li, Xiaoting, Xu, Zhe, Zeng, Zhichen, Liu, Lihui, Liu, Zhining, Tong, Hanghang   +8 more
openaire   +2 more sources

Enhancing Molecular Network‐Based Cancer Driver Gene Prediction Using Machine Learning Approaches: Current Challenges and Opportunities

Journal of Cellular and Molecular Medicine, Volume 29, Issue 1, January 2025.
ABSTRACT Cancer is a complex disease driven by mutations in the genes that play critical roles in cellular processes. The identification of cancer driver genes is crucial for understanding tumorigenesis, developing targeted therapies and identifying rational drug targets.
Hao Zhang, Chaohuan Lin, Ying'ao Chen, Xianrui Shen, Ruizhe Wang, Yiqi Chen, Jie Lyu   +6 more
wiley   +1 more source

Learning Laplacian Positional Encodings for Heterophilous Graphs

CoRR
AISTATS 2025; version with full ...
Michael Ito, Jiong Zhu, Dexiong Chen, Danai Koutra, Jenna Wiens   +4 more
openaire   +3 more sources

Data‐efficient graph learning: Problems, progress, and prospects

AI Magazine, Volume 45, Issue 4, Page 549-560, Winter 2024.
Abstract Graph‐structured data, ranging from social networks to financial transaction networks, from citation networks to gene regulatory networks, have been widely used for modeling a myriad of real‐world systems. As a prevailing model architecture to model graph‐structured data, graph neural networks (GNNs) have drawn much attention in both academic ...
Kaize Ding, Yixin Liu, Chuxu Zhang, Jianling Wang   +3 more
wiley   +1 more source