Results 231 to 240 of about 5,571 (281)

Mapping Alkyne Chemical Space—Classifying the Reactivity of Alkynes in Semihydrogenation and beyond Using a Data Science Framework

open access: yesHelvetica Chimica Acta, EarlyView.
A data science framework integrating DFT featurization and hierarchical clustering was used to map the chemical space of over 2700 alkynes into six subsets before using experimental data for Ni3Zn‐catalyzed semihydrogenation and applying a logistic regression model to categorize substrates by reactivity.
Jordan De Jesus Silva   +5 more
wiley   +1 more source

ID3 deficiency alters chromatin accessibility at DSB sites and enhances vulnerability to HDAC inhibition

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Errors in DNA double‐strand break (DSB) repair can lead to mutations, chromosomal instability, and ultimately cancer. Inhibitor of DNA‐binding 3 (ID3), a transcriptional repressor, is crucial to promoting DSB repair and helping maintain genome stability. Here, the authors investigated ID3 regulation of DNA repair via chromatin accessibility
Giuditta Della Corte   +10 more
wiley   +1 more source

Heterotaxy syndrome with biliary atresia: a case report. [PDF]

open access: yesPan Afr Med J
Khazi AI   +3 more
europepmc   +1 more source

Unleashing the Potential of Generalist Segmentation Foundation Models for Biomedical Image and Video Analysis

open access: yesiRADIOLOGY, EarlyView.
Generalist segmentation models such as SAM and SAM2 show promise in biomedical imaging but face challenges such as domain shift and ambiguous boundaries. Future efforts should focus on specialized adaptation for clinical translation. Imaging data are derived from the public datasets AbdomenAtlas and BraTS19.
Yichi Zhang   +4 more
wiley   +1 more source

Deep Learning Integration in Optical Microscopy: Advancements and Applications

open access: yesMicroscopy Research and Technique, EarlyView.
It explores the integration of DL into optical microscopy, focusing on key applications including image classification, segmentation, and computational reconstruction. ABSTRACT Optical microscopy is a cornerstone imaging technique in biomedical research, enabling visualization of subcellular structures beyond the resolution limit of the human eye ...
Pottumarthy Venkata Lahari   +5 more
wiley   +1 more source

Channeling of the pulmonary veins in a 5-month-old patient with complex heterotaxy and atrioventricular discordance. [PDF]

open access: yesJTCVS Tech
Le L   +7 more
europepmc   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy   +7 more
wiley   +1 more source

How Early Veno-Venous Malformation Can Jeopardize a Perfect Kawashima Repair: A Compilation of Two Cases and Review of Literature. [PDF]

open access: yesCureus
Talwar S   +14 more
europepmc   +1 more source

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