Results 91 to 100 of about 4,442 (232)

A breviloquent description about the challenges involved and the management strategies for the complex cardiac abnormality — Ivemark syndrome

Journal of Rare Diseases
Ivemark syndrome, a classification of heterotaxy syndrome, is an extremely uncommon congenital condition. An aberrant configuration of the thoracoabdominal organs across the body’s left–right axis is known as heterotaxy, and it is always linked to either
Pooja C., Sankari A., Sashtipriyaa R., Mariyam Susan Joji, Sarumathy S.   +4 more
doaj   +1 more source

Evidence of emerging transcriptome mediators of Alzheimer's disease in canine cognitive dysfunction

Brain Pathology, EarlyView.
Canine cognitive dysfunction (CCD) may be a promising model of Alzheimer's disease (AD). To assess AD‐related molecular signatures in CCD, we generated transcriptome data on dog cortex and plasma extracellular vesicles (EVs). CCD‐related transcriptome changes were similar to those in aging/AD humans and were detectable in EVs from the same animals ...
Shelby C. Osburn, Darby S. Easterday, Cali M. McEntee, Amanda S. Latham, Daniel S. Lark, Stephanie McGrath, Julie A. Moreno, Thomas J. LaRocca   +7 more
wiley   +1 more source

Primary Ciliary Dyskinesia and Hydrocephalus With Aqueductal Stenosis [PDF]

, 2011
We report 1 female patient with situs inversus, dextrocardia, a complex heart malformation, hydrocephalus due to aqueductal stenosis, and abnormal ultrastructure of the respiratory epithelium cilia.
Lopes, P, Silva, R, Vieira, JP
core  

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source

Kawashima operation: functional modification of bidirectional Glen shunt with left superior vena cava in single ventricular morphology [PDF]

, 2009
Single ventricle physiology offers limited options with significant morbidity and mortality. The Glenn shunt is a mid-stage procedure for the Fontan circulation.
Amanullah, Muneer, Atiq, Mehnaz, Fatimi, Saulat, Shahabuddin, Syed   +3 more
core   +1 more source

Bronchiectasis:a case-based approach to investigation and management [PDF]

, 2018
Bronchiectasis is a chronic respiratory disease characterised by a syndrome of productive cough and recurrent respiratory infections due to permanent dilatation of the bronchi.
Agarwal, Agarwal, Bonaiti, Cartier, Chu, Cole, Erasmus, Farrell, Greenberger, Gremmo, Hosie, James D. Chalmers, Martina Contarini, Mirsaeidi, Neeld, Nicolini, Shapiro, Simon Finch   +17 more
core   +3 more sources

Prevalence and Spectrum of Congenital Heart Disease in Individuals With Distal Chromosome 22q11.22–23 Deletions

Clinical Genetics, EarlyView.
The frequency and severity of congenital heart disease vary extensively in individuals with 22q11.22–23 distal deletions. Reduced gene dosage particularly within the low copy repeat (LCR22) D–E region including MAPK1 and HIC2 conveys risk for these defects.
Tanner J. Nelson, Daniel E. McGinn, T. Blaine Crowley, Lydia Rockart, Audrey Green, Victoria Giunta, Oanh Tran, Daniella Miller, Jeroen Breckpot, Ann Swillen, M. Cristina Digilio, Marta Unolt, Carolina Putotto, Federica Pulvirenti, Bruno Marino, Beverly S. Emanuel, Elaine H. Zackai, Zhengdong D. Zhang, Elizabeth Goldmuntz, Erik Boot, Anne S. Bassett, Bernice E. Morrow, Donna M. McDonald‐McGinn   +22 more
wiley   +1 more source

A Han-Chinese Fetus With Heterotaxy Syndrome Caused by Novel Compound Heterozygous Mutations in PKD1L1: A Case Report

Clinical and Experimental Obstetrics & Gynecology
Background: Heterotaxy syndrome is characterized by abnormal organ arrangement across the left-right (L-R) axis, often leading to complex congenital heart defects (CHDs).
Xinyuan Teng, Jiayao Zhao, Jiayu Shen, Jin Yao, Liangfang Tang, Jingwei Xu, Yi Chen, Liquan Wang   +7 more
doaj   +1 more source

Polysplenia syndrome with situs ambiguous, common mesentery, and IVC interruption discovered incidentally in an adult

Radiology Case Reports, 2019
Polysplenia syndrome associates multiple spleens to other malformations, most frequently cardiac, vascular, visceral, and biliary malformations. Polysplenia has been described mainly in childhood owing to critical anatomic malformations related to ...
Hajar El Mortaji, Kenza Elatiqi, Hanane El Hammaoui, Soumaya Alj   +3 more
doaj   +1 more source

PIERCE1 is critical for specification of left-right asymmetry in mice. [PDF]

The specification of left-right asymmetry of the visceral organs is precisely regulated. The earliest breakage of left-right symmetry occurs as the result of leftward flow generated by asymmetric beating of nodal cilia, which eventually induces ...
Baek, IJ, Gho, YS, Kim, YH, Lee, HW, Lee, YJ, Oh, SP, Sung, YH   +6 more
core   +1 more source