Results 101 to 110 of about 4,489 (232)

Diving Deeper Into Mechanisms of Acrylamide‐Induced Toxicity: RNA Sequencing Reveals Transcriptomic Alteration and Retrotransposon Expression in Drosophila melanogaster

Environmental Toxicology, EarlyView.
ABSTRACT Given the inevitability of human and animal exposure to acrylamide, there is increasing concern regarding its potential health risks. While a number of molecular mechanisms have been proposed, the complexity of acrylamide toxicological pathways and interactions remains incompletely characterized.
Oluwabukola Mary Farodoye, Titilayomi Ayomide Otenaike, Daniela Moreira Mombach, Monica Medeiros Silva, Amos Olalekan Abolaji, Elgion Lucio Da Silva Loreto   +5 more
wiley   +1 more source

A breviloquent description about the challenges involved and the management strategies for the complex cardiac abnormality — Ivemark syndrome

Journal of Rare Diseases
Ivemark syndrome, a classification of heterotaxy syndrome, is an extremely uncommon congenital condition. An aberrant configuration of the thoracoabdominal organs across the body’s left–right axis is known as heterotaxy, and it is always linked to either
Pooja C., Sankari A., Sashtipriyaa R., Mariyam Susan Joji, Sarumathy S.   +4 more
doaj   +1 more source

Prenatal detection and outcome of major heart defects in a country with universal screening

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To evaluate the Danish prenatal screening program for major fetal congenital heart defects (mCHD), focusing on incidence, detection rates (DRs), pregnancy outcomes and postnatal mortality. Methods This was a 5‐year nationwide cohort study conducted from January 2018 to December 2022 in Denmark.
C. Vedel, J. Steensberg, O. B. Petersen, H. Andersen, M. Barbosa, M. Christiansen, V. Gjørup, A. N. Jensen, K. Munk, K. Nyborg, A. W. Olesen, F. Ravn, L. Sperling, H. G. H. Thyregod, N. Vejlstrup, C. K. Ekelund   +15 more
wiley   +1 more source

The inferior caval vein draining into the left atrial cavity : a rare case [PDF]

, 2011
The inferior vena cava (IVC) draining into the left atrium (LA) is exceedingly rare in the setting of the usual atrial arrangement (situs solitus).
McCarthy, Karen, Shiina, Y., Slavik, S., Uemura, H., Yen Ho, S.   +4 more
core  

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

The Current Landscape of Genetic Testing in Cardiovascular Malformations: Opportunities and Challenges [PDF]

, 2016
Human cardiovascular malformations (CVMs) frequently have a genetic contribution. Through the application of novel technologies, such as next-generation sequencing, DNA sequence variants associated with CVMs are being identified at a rapid pace.
Landis, Benjamin J., Ware, Stephanie M.
core   +2 more sources

Desired and Feared Identities and Their Role in Occupational Identity Regulation

Journal of Management Studies, EarlyView.
Abstract This paper extends theory by showing how occupational identity regulation operates jointly through both desired and feared identities which, in combination, enforce normative control. Taking a narrative identity perspective and drawing on an ethnographic and interview‐based study of veterinarians, we make three principal contributions to our ...
Sarah Page‐Jones, Andrew D. Brown
wiley   +1 more source

A Han-Chinese Fetus With Heterotaxy Syndrome Caused by Novel Compound Heterozygous Mutations in PKD1L1: A Case Report

Clinical and Experimental Obstetrics & Gynecology
Background: Heterotaxy syndrome is characterized by abnormal organ arrangement across the left-right (L-R) axis, often leading to complex congenital heart defects (CHDs).
Xinyuan Teng, Jiayao Zhao, Jiayu Shen, Jin Yao, Liangfang Tang, Jingwei Xu, Yi Chen, Liquan Wang   +7 more
doaj   +1 more source

The Evolving Landscape of CHD Genetics: A Contemporary Guide to Genetic Testing and Management

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Congenital heart disease (CHD) is the most common birth defect, affecting an estimated 9.4/1000 infants globally. The genetics of CHD is complex, with most cases thought to have multifactorial aetiology, implicating both genetic and environmental factors.
Bridget R. O'Malley, Gary F. Sholler, Janine Smith, Gillian M. Blue   +3 more
wiley   +1 more source

Polysplenia syndrome with situs ambiguous, common mesentery, and IVC interruption discovered incidentally in an adult

Radiology Case Reports, 2019
Polysplenia syndrome associates multiple spleens to other malformations, most frequently cardiac, vascular, visceral, and biliary malformations. Polysplenia has been described mainly in childhood owing to critical anatomic malformations related to ...
Hajar El Mortaji, Kenza Elatiqi, Hanane El Hammaoui, Soumaya Alj   +3 more
doaj   +1 more source