Results 151 to 160 of about 15,687,915 (207)

The BEACH Protein LRBA Promotes the Localization of the Heterotrimeric G-protein Golf to Olfactory Cilia. [PDF]

open access: yesSci Rep, 2017
Kurtenbach S   +11 more
europepmc   +1 more source

Direct Modulation of Heterotrimeric G Protein-coupled Signaling by a Receptor Kinase Complex. [PDF]

open access: yesJ Biol Chem, 2016
Tunc-Ozdemir M   +4 more
europepmc   +1 more source
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Heterotrimeric G proteins

Current Opinion in Cell Biology, 1996
Over the past year, the thrust of work in the field of heterotrimeric G proteins has been primarily in the following areas: first, resolution of their three-dimensional structures by X-ray crystallography; second, elucidation of the effect of lipid modifications on the Galpha and Ggamma subunits; third, understanding the role of the Gbetagamma dimer in
H E, Hamm, A, Gilchrist
openaire   +3 more sources

Heterotrimeric G Proteins and Microtubules

2013
Microtubules, major components of the cytoskeleton, play important roles in a variety of cellular functions including mitosis, intracellular transport, and the modulation of cell morphology. Several studies have demonstrated that specific G-protein alpha subunits bind to tubulin with a high affinity (~130 nM) and elicit various functional effects on ...
Witchuda, Saengsawang, Mark M, Rasenick
openaire   +2 more sources

Heterotrimeric G-proteins and development

Biochemical Pharmacology, 1997
Heterotrimeric G-proteins are well-known transducers of signaling from a populous class of heptihelical, membrane receptors to a smaller group of effector molecules that includes adenylylcyclases, cyclic GMP phosphodiesterases, phospholipases (type C beta), and various ion channels.
openaire   +2 more sources

Heterotrimeric G Protein Activation by G-Protein-Coupled Receptors

Nature Reviews Molecular Cell Biology, 2008
Heterotrimeric G proteins have a crucial role as molecular switches in signal transduction pathways mediated by G-protein-coupled receptors. Extracellular stimuli activate these receptors, which then catalyse GTP-GDP exchange on the G protein alpha-subunit.
Heidi E. Hamm, William M Oldham
exaly   +3 more sources

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